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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD3
All Species:
14.85
Human Site:
Y439
Identified Species:
27.22
UniProt:
Q12873
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12873
NP_001005271.2
2000
226592
Y439
A
K
E
E
E
E
E
Y
E
E
E
G
E
E
E
Chimpanzee
Pan troglodytes
XP_512012
1846
210165
Y434
A
K
E
E
E
E
E
Y
E
E
E
G
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001111066
1981
224269
Y439
A
K
E
E
E
E
E
Y
E
E
E
G
E
E
E
Dog
Lupus familis
XP_536627
1977
223828
Y417
A
K
E
E
E
E
E
Y
E
E
G
E
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDQ2
1915
217732
G423
A
K
E
D
N
S
E
G
E
E
I
L
E
E
V
Rat
Rattus norvegicus
Q9JIX5
2581
290674
G498
S
V
R
P
E
E
E
G
E
K
K
R
R
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q06A37
3011
338194
K650
Q
E
D
K
K
K
K
K
K
P
K
A
K
K
E
Frog
Xenopus laevis
NP_001080504
1893
214670
L421
A
K
E
D
N
S
E
L
D
D
D
L
D
D
A
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
I568
S
K
T
K
L
N
T
I
T
L
V
G
K
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
E435
A
E
E
E
D
D
D
E
H
Q
E
F
C
R
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
D356
S
Y
H
A
Y
C
I
D
P
P
L
T
E
I
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
H72
N
T
C
T
Y
A
F
H
A
K
C
L
V
P
P
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
S155
E
S
E
D
D
Y
G
S
E
E
A
L
S
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
97.8
97.3
N.A.
67.6
22.6
N.A.
N.A.
23.4
66
22.7
N.A.
55
N.A.
47.2
N.A.
Protein Similarity:
100
90.5
98.1
98
N.A.
78.3
37.6
N.A.
N.A.
37.2
77.1
38.5
N.A.
68.6
N.A.
61.7
N.A.
P-Site Identity:
100
100
100
80
N.A.
53.3
26.6
N.A.
N.A.
6.6
26.6
13.3
N.A.
26.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
60
60
N.A.
N.A.
73.3
66.6
40
N.A.
60
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.6
40.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
0
8
0
8
0
0
8
0
8
8
0
0
8
% A
% Cys:
0
0
8
0
0
8
0
0
0
0
8
0
8
0
0
% C
% Asp:
0
0
8
24
16
8
8
8
8
8
8
0
8
8
0
% D
% Glu:
8
16
62
39
39
39
54
8
54
47
31
8
47
47
39
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
16
0
0
8
31
0
0
8
% G
% His:
0
0
8
0
0
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
8
0
0
8
0
0
8
0
% I
% Lys:
0
54
0
16
8
8
8
8
8
16
16
0
16
24
8
% K
% Leu:
0
0
0
0
8
0
0
8
0
8
8
31
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
16
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
8
16
0
0
0
8
16
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
8
8
8
8
% R
% Ser:
24
8
0
0
0
16
0
8
0
0
0
0
8
0
0
% S
% Thr:
0
8
8
8
0
0
8
0
8
0
0
8
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
8
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
16
8
0
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _