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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD3 All Species: 15.15
Human Site: Y578 Identified Species: 27.78
UniProt: Q12873 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12873 NP_001005271.2 2000 226592 Y578 E I F H L V M Y R N Y Q R K N
Chimpanzee Pan troglodytes XP_512012 1846 210165 Y573 E I F H L V M Y R N Y Q R K N
Rhesus Macaque Macaca mulatta XP_001111066 1981 224269 Y578 E I F H L V M Y R N Y Q R K N
Dog Lupus familis XP_536627 1977 223828 Y555 E I F H L V M Y R N Y Q R K N
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 V562 Q L E L H C Q V M F R N Y Q R
Rat Rattus norvegicus Q9JIX5 2581 290674 M650 I V D K V L S M R V V K K E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 A798 E Q Q E S A D A E G P V V E K
Frog Xenopus laevis NP_001080504 1893 214670 M560 L E L H C Q V M F R N Y Q R K
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 S687 A I V D K I L S M R V T K K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 D559 R S F Q R K Y D M E E P P K F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 V455 D V Y F T A L V R M Y W R K V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 N166 H R L K T R V N N F H R Q M E
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 F249 L D N Y C K Q F I I E D Q Q V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.3 97.8 97.3 N.A. 67.6 22.6 N.A. N.A. 23.4 66 22.7 N.A. 55 N.A. 47.2 N.A.
Protein Similarity: 100 90.5 98.1 98 N.A. 78.3 37.6 N.A. N.A. 37.2 77.1 38.5 N.A. 68.6 N.A. 61.7 N.A.
P-Site Identity: 100 100 100 100 N.A. 0 6.6 N.A. N.A. 6.6 6.6 13.3 N.A. 13.3 N.A. 26.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 20 46.6 N.A. N.A. 13.3 26.6 33.3 N.A. 13.3 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 26 N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 40.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 16 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 16 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 8 8 0 0 8 8 0 0 0 8 0 0 0 % D
% Glu: 39 8 8 8 0 0 0 0 8 8 16 0 0 16 16 % E
% Phe: 0 0 39 8 0 0 0 8 8 16 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % G
% His: 8 0 0 39 8 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 8 39 0 0 0 8 0 0 8 8 0 0 0 0 0 % I
% Lys: 0 0 0 16 8 16 0 0 0 0 0 8 16 54 16 % K
% Leu: 16 8 16 8 31 8 16 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 31 16 24 8 0 0 0 8 0 % M
% Asn: 0 0 8 0 0 0 0 8 8 31 8 8 0 0 31 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 8 8 0 0 % P
% Gln: 8 8 8 8 0 8 16 0 0 0 0 31 24 16 0 % Q
% Arg: 8 8 0 0 8 8 0 0 47 16 8 8 39 8 8 % R
% Ser: 0 8 0 0 8 0 8 8 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 16 0 0 0 0 0 0 8 0 0 0 % T
% Val: 0 16 8 0 8 31 16 16 0 8 16 8 8 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 8 8 0 0 8 31 0 0 39 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _