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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD3
All Species:
26.36
Human Site:
Y658
Identified Species:
48.33
UniProt:
Q12873
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12873
NP_001005271.2
2000
226592
Y658
V
K
W
R
D
L
P
Y
D
Q
S
T
W
E
E
Chimpanzee
Pan troglodytes
XP_512012
1846
210165
Y653
V
K
W
R
D
L
P
Y
D
Q
S
T
W
E
E
Rhesus Macaque
Macaca mulatta
XP_001111066
1981
224269
Y658
V
K
W
R
D
L
P
Y
D
Q
S
T
W
E
E
Dog
Lupus familis
XP_536627
1977
223828
Y635
V
K
W
R
D
L
P
Y
D
Q
S
T
W
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDQ2
1915
217732
Y642
I
K
W
R
D
L
P
Y
D
Q
A
S
W
E
S
Rat
Rattus norvegicus
Q9JIX5
2581
290674
L730
Y
V
E
V
D
R
I
L
D
E
S
H
S
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q06A37
3011
338194
F878
S
E
I
D
D
E
L
F
N
P
D
Y
V
E
I
Frog
Xenopus laevis
NP_001080504
1893
214670
Y640
I
K
W
R
D
L
A
Y
D
Q
A
S
W
E
A
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
D767
V
E
V
D
R
I
L
D
E
S
H
S
V
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
Y639
V
K
W
R
E
L
P
Y
D
K
S
T
W
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
R535
Y
E
H
A
T
W
E
R
D
D
T
D
I
A
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
R246
D
V
N
S
R
T
R
R
S
K
D
V
D
H
K
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
K329
E
N
A
T
D
I
V
K
L
A
P
E
Q
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
97.8
97.3
N.A.
67.6
22.6
N.A.
N.A.
23.4
66
22.7
N.A.
55
N.A.
47.2
N.A.
Protein Similarity:
100
90.5
98.1
98
N.A.
78.3
37.6
N.A.
N.A.
37.2
77.1
38.5
N.A.
68.6
N.A.
61.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
73.3
20
N.A.
N.A.
13.3
66.6
6.6
N.A.
86.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
33.3
N.A.
N.A.
33.3
86.6
46.6
N.A.
100
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.6
40.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
8
0
0
8
16
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
16
70
0
0
8
70
8
16
8
8
8
8
% D
% Glu:
8
24
8
0
8
8
8
0
8
8
0
8
0
62
39
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
8
8
0
8
0
% H
% Ile:
16
0
8
0
0
16
8
0
0
0
0
0
8
0
8
% I
% Lys:
0
54
0
0
0
0
0
8
0
16
0
0
0
0
24
% K
% Leu:
0
0
0
0
0
54
16
8
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
8
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
47
0
0
8
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
47
0
0
8
0
0
% Q
% Arg:
0
0
0
54
16
8
8
16
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
8
0
0
0
0
8
8
47
24
8
0
8
% S
% Thr:
0
0
0
8
8
8
0
0
0
0
8
39
0
0
0
% T
% Val:
47
16
8
8
0
0
8
0
0
0
0
8
16
16
0
% V
% Trp:
0
0
54
0
0
8
0
0
0
0
0
0
54
0
0
% W
% Tyr:
16
0
0
0
0
0
0
54
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _