KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD3
All Species:
24.24
Human Site:
Y673
Identified Species:
44.44
UniProt:
Q12873
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12873
NP_001005271.2
2000
226592
Y673
D
E
M
N
I
P
E
Y
E
E
H
K
Q
S
Y
Chimpanzee
Pan troglodytes
XP_512012
1846
210165
Y668
D
E
M
N
I
P
E
Y
E
E
H
K
Q
S
Y
Rhesus Macaque
Macaca mulatta
XP_001111066
1981
224269
Y673
D
E
M
N
I
P
E
Y
E
E
H
K
Q
S
Y
Dog
Lupus familis
XP_536627
1977
223828
Y650
D
E
M
N
I
P
E
Y
E
D
H
K
Q
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDQ2
1915
217732
Y657
E
D
V
E
I
Q
D
Y
D
L
F
K
Q
S
Y
Rat
Rattus norvegicus
Q9JIX5
2581
290674
I745
K
D
N
G
E
P
V
I
Y
Y
L
V
K
W
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q06A37
3011
338194
R893
D
R
I
L
D
F
S
R
S
T
D
D
N
G
E
Frog
Xenopus laevis
NP_001080504
1893
214670
Y655
E
E
S
D
I
Q
D
Y
D
I
Y
K
Q
G
Y
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
Y782
D
N
G
E
P
V
V
Y
Y
L
V
K
W
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
L654
E
G
D
D
I
Q
G
L
R
Q
A
I
D
Y
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
Y550
Y
E
D
A
I
I
K
Y
W
H
H
R
E
R
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
Q261
R
N
P
R
D
F
Q
Q
F
D
H
T
P
E
F
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
S344
H
F
Q
N
R
E
N
S
K
I
L
P
Q
Y
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
97.8
97.3
N.A.
67.6
22.6
N.A.
N.A.
23.4
66
22.7
N.A.
55
N.A.
47.2
N.A.
Protein Similarity:
100
90.5
98.1
98
N.A.
78.3
37.6
N.A.
N.A.
37.2
77.1
38.5
N.A.
68.6
N.A.
61.7
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
40
6.6
N.A.
N.A.
6.6
40
20
N.A.
13.3
N.A.
26.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
73.3
20
N.A.
N.A.
13.3
73.3
20
N.A.
33.3
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.6
40.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
47
16
16
16
16
0
16
0
16
16
8
8
8
0
0
% D
% Glu:
24
47
0
16
8
8
31
0
31
24
0
0
8
8
8
% E
% Phe:
0
8
0
0
0
16
0
0
8
0
8
0
0
0
8
% F
% Gly:
0
8
8
8
0
0
8
0
0
0
0
0
0
16
0
% G
% His:
8
0
0
0
0
0
0
0
0
8
47
0
0
0
0
% H
% Ile:
0
0
8
0
62
8
0
8
0
16
0
8
0
0
0
% I
% Lys:
8
0
0
0
0
0
8
0
8
0
0
54
8
0
0
% K
% Leu:
0
0
0
8
0
0
0
8
0
16
16
0
0
0
0
% L
% Met:
0
0
31
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
16
8
39
0
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
8
0
8
39
0
0
0
0
0
8
8
0
0
% P
% Gln:
0
0
8
0
0
24
8
8
0
8
0
0
54
0
0
% Q
% Arg:
8
8
0
8
8
0
0
8
8
0
0
8
0
8
0
% R
% Ser:
0
0
8
0
0
0
8
8
8
0
0
0
0
39
16
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% T
% Val:
0
0
8
0
0
8
16
0
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
0
% W
% Tyr:
8
0
0
0
0
0
0
62
16
8
8
0
0
16
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _