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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3A3
All Species:
40.61
Human Site:
S257
Identified Species:
68.72
UniProt:
Q12874
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12874
NP_006793.1
501
58849
S257
S
S
W
E
E
L
A
S
L
G
L
D
R
L
K
Chimpanzee
Pan troglodytes
XP_001170203
457
53624
G228
W
E
N
G
T
F
P
G
W
P
K
E
T
S
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849980
501
58873
S257
S
S
W
E
E
L
A
S
L
G
L
D
R
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D554
501
58823
S257
S
S
W
E
E
L
A
S
L
G
L
D
R
L
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512163
478
55587
S234
S
S
W
E
E
L
A
S
L
G
L
D
R
L
K
Chicken
Gallus gallus
XP_001232935
501
58871
S257
S
S
W
E
E
L
A
S
L
G
L
D
R
L
K
Frog
Xenopus laevis
NP_001088491
501
58735
S257
S
S
W
E
E
L
A
S
L
G
L
D
R
L
K
Zebra Danio
Brachydanio rerio
NP_001004289
501
58645
S257
S
S
W
E
E
L
A
S
L
G
L
D
R
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46106
503
58403
S257
S
S
W
E
E
L
A
S
L
G
L
D
R
L
K
Honey Bee
Apis mellifera
XP_397399
501
58338
S257
S
S
W
E
E
L
A
S
L
G
L
D
R
L
K
Nematode Worm
Caenorhab. elegans
NP_495799
500
57459
L256
P
Y
N
S
A
E
E
L
E
G
L
G
L
E
R
Sea Urchin
Strong. purpuratus
XP_782055
503
58549
S257
S
S
P
E
E
L
A
S
L
G
L
D
R
L
K
Poplar Tree
Populus trichocarpa
XP_002317774
509
59816
E258
S
T
V
E
E
L
K
E
V
G
P
E
K
L
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19736
530
63011
L251
F
F
K
S
Y
A
L
L
D
A
A
A
V
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.2
N.A.
99.8
N.A.
99.1
N.A.
N.A.
92.8
97
91.8
91
N.A.
65.4
72.2
52.6
72.7
Protein Similarity:
100
91.2
N.A.
99.8
N.A.
99.5
N.A.
N.A.
93.8
98.8
97
95.6
N.A.
81.3
85
71.2
86.6
P-Site Identity:
100
0
N.A.
100
N.A.
100
N.A.
N.A.
100
100
100
100
N.A.
100
100
13.3
93.3
P-Site Similarity:
100
6.6
N.A.
100
N.A.
100
N.A.
N.A.
100
100
100
100
N.A.
100
100
20
93.3
Percent
Protein Identity:
45.1
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
66
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
46.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
72
0
0
8
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
72
0
0
0
% D
% Glu:
0
8
0
79
79
8
8
8
8
0
0
15
0
15
0
% E
% Phe:
8
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
0
86
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
8
0
0
0
8
0
8
0
79
% K
% Leu:
0
0
0
0
0
79
8
15
72
0
79
0
8
79
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
8
0
8
0
0
0
8
0
0
8
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
72
0
8
% R
% Ser:
79
72
0
15
0
0
0
72
0
0
0
0
0
8
8
% S
% Thr:
0
8
0
0
8
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
8
0
0
0
0
0
8
0
0
0
8
0
0
% V
% Trp:
8
0
65
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _