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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SF3A3 All Species: 29.09
Human Site: T314 Identified Species: 49.23
UniProt: Q12874 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12874 NP_006793.1 501 58849 T314 S K G T K R D T E R N K D I A
Chimpanzee Pan troglodytes XP_001170203 457 53624 L285 L E E R A Q R L F S T K G K S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849980 501 58873 T314 S K G T K R D T E R N K D I A
Cat Felis silvestris
Mouse Mus musculus Q9D554 501 58823 T314 S K G T K R D T E R N K D I A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512163 478 55587 T291 S K G T K R D T E R N K D I A
Chicken Gallus gallus XP_001232935 501 58871 T314 T K G I K R D T E R N K D L A
Frog Xenopus laevis NP_001088491 501 58735 T314 A K A T R R D T E K N K D I A
Zebra Danio Brachydanio rerio NP_001004289 501 58645 S314 A K G P K K D S E R N K E S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O46106 503 58403 E314 T A S A Q S R E H E R H K E I
Honey Bee Apis mellifera XP_397399 501 58338 S314 K S G K G R N S E K Q K E I A
Nematode Worm Caenorhab. elegans NP_495799 500 57459 N313 N S D A E K Q N A K N L T L A
Sea Urchin Strong. purpuratus XP_782055 503 58549 K314 G K T T K A G K K D A E K Q R
Poplar Tree Populus trichocarpa XP_002317774 509 59816 A315 G S E P N G G A A T S K E V D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P19736 530 63011 E308 G K I H K K N E S K R R N F V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.2 N.A. 99.8 N.A. 99.1 N.A. N.A. 92.8 97 91.8 91 N.A. 65.4 72.2 52.6 72.7
Protein Similarity: 100 91.2 N.A. 99.8 N.A. 99.5 N.A. N.A. 93.8 98.8 97 95.6 N.A. 81.3 85 71.2 86.6
P-Site Identity: 100 6.6 N.A. 100 N.A. 100 N.A. N.A. 100 80 73.3 60 N.A. 0 40 13.3 20
P-Site Similarity: 100 26.6 N.A. 100 N.A. 100 N.A. N.A. 100 93.3 93.3 86.6 N.A. 13.3 66.6 46.6 33.3
Percent
Protein Identity: 45.1 N.A. N.A. N.A. 24.5 N.A.
Protein Similarity: 66 N.A. N.A. N.A. 44.1 N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 8 15 8 8 0 8 15 0 8 0 0 0 65 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 50 0 0 8 0 0 43 0 8 % D
% Glu: 0 8 15 0 8 0 0 15 58 8 0 8 22 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % F
% Gly: 22 0 50 0 8 8 15 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 8 0 0 0 0 8 0 0 8 0 0 0 % H
% Ile: 0 0 8 8 0 0 0 0 0 0 0 0 0 43 8 % I
% Lys: 8 65 0 8 58 22 0 8 8 29 0 72 15 8 0 % K
% Leu: 8 0 0 0 0 0 0 8 0 0 0 8 0 15 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 8 0 15 8 0 0 58 0 8 0 0 % N
% Pro: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 8 8 0 0 0 8 0 0 8 0 % Q
% Arg: 0 0 0 8 8 50 15 0 0 43 15 8 0 0 8 % R
% Ser: 29 22 8 0 0 8 0 15 8 8 8 0 0 8 8 % S
% Thr: 15 0 8 43 0 0 0 43 0 8 8 0 8 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _