KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAP
All Species:
24.85
Human Site:
S116
Identified Species:
49.7
UniProt:
Q12884
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12884
NP_004451.2
760
87713
S116
R
Q
F
V
Y
L
E
S
D
Y
S
K
L
W
R
Chimpanzee
Pan troglodytes
Q5IS50
803
91393
Y143
R
E
Y
A
L
F
S
Y
N
V
E
P
I
Y
Q
Rhesus Macaque
Macaca mulatta
XP_001096858
760
87738
S116
R
Q
F
V
Y
L
E
S
D
Y
S
K
L
W
R
Dog
Lupus familis
XP_850205
760
87694
S116
R
Q
F
A
Y
L
E
S
D
Y
S
K
L
W
R
Cat
Felis silvestris
Mouse
Mus musculus
P97321
761
87926
S116
R
Q
F
V
Y
L
E
S
D
Y
S
K
L
W
R
Rat
Rattus norvegicus
P14740
767
88070
Y116
R
L
F
V
L
L
E
Y
N
Y
V
K
Q
W
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512952
760
87513
D116
Q
F
A
F
L
E
S
D
Y
S
K
L
W
R
Y
Chicken
Gallus gallus
NP_001026426
759
86325
Y116
Q
R
F
A
L
L
Q
Y
K
Y
E
K
L
W
R
Frog
Xenopus laevis
NP_001079272
755
86900
K116
L
L
L
E
S
N
Y
K
K
Q
W
R
Y
S
Y
Zebra Danio
Brachydanio rerio
XP_001920834
793
90752
S156
R
K
F
A
A
F
E
S
N
Y
S
K
Q
W
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18253
829
94369
K162
M
K
Y
A
Y
G
S
K
K
V
N
E
L
W
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P18962
818
93386
H135
L
E
G
K
T
F
I
H
N
G
Q
N
L
T
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.2
99.6
93.4
N.A.
89.6
52.7
N.A.
83.9
55.1
58
49.8
N.A.
N.A.
N.A.
28.3
N.A.
Protein Similarity:
100
54.1
99.7
97.5
N.A.
94.4
72.4
N.A.
92.3
72.5
75.2
68.7
N.A.
N.A.
N.A.
44.3
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
100
60
N.A.
0
46.6
0
60
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
46.6
100
93.3
N.A.
100
66.6
N.A.
6.6
66.6
6.6
73.3
N.A.
N.A.
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
42
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
34
0
0
0
0
0
0
% D
% Glu:
0
17
0
9
0
9
50
0
0
0
17
9
0
0
0
% E
% Phe:
0
9
59
9
0
25
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
9
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% I
% Lys:
0
17
0
9
0
0
0
17
25
0
9
59
0
0
0
% K
% Leu:
17
17
9
0
34
50
0
0
0
0
0
9
59
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
34
0
9
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
17
34
0
0
0
0
9
0
0
9
9
0
17
0
9
% Q
% Arg:
59
9
0
0
0
0
0
0
0
0
0
9
0
9
67
% R
% Ser:
0
0
0
0
9
0
25
42
0
9
42
0
0
9
0
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% T
% Val:
0
0
0
34
0
0
0
0
0
17
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
9
67
0
% W
% Tyr:
0
0
17
0
42
0
9
25
9
59
0
0
9
9
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _