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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAP All Species: 26.97
Human Site: T391 Identified Species: 53.94
UniProt: Q12884 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12884 NP_004451.2 760 87713 T391 V E N A I Q I T S G K W E A I
Chimpanzee Pan troglodytes Q5IS50 803 91393 T419 N D N I Q S I T S G D W D V T
Rhesus Macaque Macaca mulatta XP_001096858 760 87738 T391 V E N A I Q I T S G K W E A I
Dog Lupus familis XP_850205 760 87694 T391 V E N A I Q I T S G K W E A I
Cat Felis silvestris
Mouse Mus musculus P97321 761 87926 T391 V E N A I Q I T S G K W E A I
Rat Rattus norvegicus P14740 767 88070 T396 R K P E Q V C T F I T K G A W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512952 760 87513 T390 V E N A V Q I T S G Q W E A I
Chicken Gallus gallus NP_001026426 759 86325 T391 T E A P V P I T E G K W E V I
Frog Xenopus laevis NP_001079272 755 86900 T388 K E K A I P I T H G N W E A F
Zebra Danio Brachydanio rerio XP_001920834 793 90752 E428 P I T S G K W E V I Y I S K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18253 829 94369 E458 K I T K W I G E N F D V I L V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P18962 818 93386 I452 M E N R L Y F I S T R K S S T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.2 99.6 93.4 N.A. 89.6 52.7 N.A. 83.9 55.1 58 49.8 N.A. N.A. N.A. 28.3 N.A.
Protein Similarity: 100 54.1 99.7 97.5 N.A. 94.4 72.4 N.A. 92.3 72.5 75.2 68.7 N.A. N.A. N.A. 44.3 N.A.
P-Site Identity: 100 40 100 100 N.A. 100 13.3 N.A. 86.6 53.3 60 0 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 53.3 100 100 N.A. 100 20 N.A. 100 60 60 20 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 50 0 0 0 0 0 0 0 0 0 59 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 17 0 9 0 0 % D
% Glu: 0 67 0 9 0 0 0 17 9 0 0 0 59 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 9 9 0 0 0 0 9 % F
% Gly: 0 0 0 0 9 0 9 0 0 67 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 17 0 9 42 9 67 9 0 17 0 9 9 0 50 % I
% Lys: 17 9 9 9 0 9 0 0 0 0 42 17 0 9 0 % K
% Leu: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 59 0 0 0 0 0 9 0 9 0 0 0 0 % N
% Pro: 9 0 9 9 0 17 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 17 42 0 0 0 0 9 0 0 0 0 % Q
% Arg: 9 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % R
% Ser: 0 0 0 9 0 9 0 0 59 0 0 0 17 9 0 % S
% Thr: 9 0 17 0 0 0 0 75 0 9 9 0 0 0 17 % T
% Val: 42 0 0 0 17 9 0 0 9 0 0 9 0 17 17 % V
% Trp: 0 0 0 0 9 0 9 0 0 0 0 67 0 0 9 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _