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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAP
All Species:
30
Human Site:
T452
Identified Species:
60
UniProt:
Q12884
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12884
NP_004451.2
760
87713
T452
K
E
R
C
Q
Y
Y
T
A
S
F
S
D
Y
A
Chimpanzee
Pan troglodytes
Q5IS50
803
91393
S480
N
C
T
Y
F
S
A
S
F
S
H
S
M
D
F
Rhesus Macaque
Macaca mulatta
XP_001096858
760
87738
T452
K
E
R
C
Q
Y
Y
T
A
S
F
S
D
Y
A
Dog
Lupus familis
XP_850205
760
87694
T452
K
E
R
C
Q
Y
Y
T
A
S
F
S
D
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
P97321
761
87926
T452
K
E
R
C
Q
Y
Y
T
A
S
F
S
Y
K
A
Rat
Rattus norvegicus
P14740
767
88070
Y457
L
N
P
E
R
C
Q
Y
Y
S
V
S
L
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512952
760
87513
T451
K
E
R
C
Q
Y
Y
T
A
S
F
S
N
S
A
Chicken
Gallus gallus
NP_001026426
759
86325
S452
Q
E
R
C
Q
Y
Y
S
A
S
F
S
K
D
A
Frog
Xenopus laevis
NP_001079272
755
86900
T449
K
E
R
C
Q
Y
Y
T
A
R
F
S
H
K
A
Zebra Danio
Brachydanio rerio
XP_001920834
793
90752
S489
Q
Y
N
S
A
Y
F
S
L
N
A
S
Y
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18253
829
94369
S519
E
D
C
K
T
L
G
S
Q
S
A
D
P
T
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P18962
818
93386
D513
V
P
Y
Q
K
I
V
D
F
H
S
R
K
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.2
99.6
93.4
N.A.
89.6
52.7
N.A.
83.9
55.1
58
49.8
N.A.
N.A.
N.A.
28.3
N.A.
Protein Similarity:
100
54.1
99.7
97.5
N.A.
94.4
72.4
N.A.
92.3
72.5
75.2
68.7
N.A.
N.A.
N.A.
44.3
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
86.6
13.3
N.A.
86.6
73.3
80
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
20
100
100
N.A.
86.6
20
N.A.
93.3
86.6
80
46.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
9
0
59
0
17
0
0
9
59
% A
% Cys:
0
9
9
59
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
9
0
0
0
9
25
17
0
% D
% Glu:
9
59
0
9
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
9
0
9
0
17
0
59
0
0
9
9
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
9
0
9
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
50
0
0
9
9
0
0
0
0
0
0
0
17
17
9
% K
% Leu:
9
0
0
0
0
9
0
0
9
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
9
9
9
0
0
0
0
0
0
9
0
0
9
0
0
% N
% Pro:
0
9
9
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
17
0
0
9
59
0
9
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
59
0
9
0
0
0
0
9
0
9
0
0
9
% R
% Ser:
0
0
0
9
0
9
0
34
0
75
9
84
0
17
0
% S
% Thr:
0
0
9
0
9
0
0
50
0
0
0
0
0
9
0
% T
% Val:
9
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
9
0
67
59
9
9
0
0
0
17
25
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _