Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAP All Species: 26.06
Human Site: Y133 Identified Species: 52.12
UniProt: Q12884 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12884 NP_004451.2 760 87713 Y133 Y T A T Y Y I Y D L S N G E F
Chimpanzee Pan troglodytes Q5IS50 803 91393 S160 Y T G Y Y V L S K I P H G D P
Rhesus Macaque Macaca mulatta XP_001096858 760 87738 Y133 Y T A T Y Y I Y D L S N G E F
Dog Lupus familis XP_850205 760 87694 Y133 Y T A T Y H I Y N L N N G E F
Cat Felis silvestris
Mouse Mus musculus P97321 761 87926 Y133 Y T A T Y Y I Y D L Q N G E F
Rat Rattus norvegicus P14740 767 88070 Y133 Y T A S Y S I Y D L N K R Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512952 760 87513 D133 T A S Y Y I Y D L G N G D F V
Chicken Gallus gallus NP_001026426 759 86325 Y133 Y T A S Y H I Y D F N T S S I
Frog Xenopus laevis NP_001079272 755 86900 E133 S Y H I Y D I E N G R F V T E
Zebra Danio Brachydanio rerio XP_001920834 793 90752 Y173 F T A S Y S I Y N V E S G E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18253 829 94369 V179 A E Y L Y H I V K I N N K T V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P18962 818 93386 K152 I T A S P D L K R L L I R T N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.2 99.6 93.4 N.A. 89.6 52.7 N.A. 83.9 55.1 58 49.8 N.A. N.A. N.A. 28.3 N.A.
Protein Similarity: 100 54.1 99.7 97.5 N.A. 94.4 72.4 N.A. 92.3 72.5 75.2 68.7 N.A. N.A. N.A. 44.3 N.A.
P-Site Identity: 100 26.6 100 80 N.A. 93.3 53.3 N.A. 6.6 46.6 13.3 53.3 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 53.3 100 100 N.A. 93.3 73.3 N.A. 20 66.6 20 86.6 N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 67 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 17 0 9 42 0 0 0 9 9 0 % D
% Glu: 0 9 0 0 0 0 0 9 0 0 9 0 0 42 9 % E
% Phe: 9 0 0 0 0 0 0 0 0 9 0 9 0 9 42 % F
% Gly: 0 0 9 0 0 0 0 0 0 17 0 9 50 0 0 % G
% His: 0 0 9 0 0 25 0 0 0 0 0 9 0 0 0 % H
% Ile: 9 0 0 9 0 9 75 0 0 17 0 9 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 9 17 0 0 9 9 0 0 % K
% Leu: 0 0 0 9 0 0 17 0 9 50 9 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 25 0 42 42 0 0 9 % N
% Pro: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 0 9 0 % Q
% Arg: 0 0 0 0 0 0 0 0 9 0 9 0 17 0 0 % R
% Ser: 9 0 9 34 0 17 0 9 0 0 17 9 9 9 0 % S
% Thr: 9 75 0 34 0 0 0 0 0 0 0 9 0 25 0 % T
% Val: 0 0 0 0 0 9 0 9 0 9 0 0 9 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 59 9 9 17 92 25 9 59 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _