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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAP
All Species:
28.79
Human Site:
Y252
Identified Species:
57.58
UniProt:
Q12884
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12884
NP_004451.2
760
87713
Y252
P
R
T
I
N
I
P
Y
P
K
A
G
A
K
N
Chimpanzee
Pan troglodytes
Q5IS50
803
91393
Y282
P
T
V
K
P
Y
H
Y
P
K
A
G
S
E
N
Rhesus Macaque
Macaca mulatta
XP_001096858
760
87738
Y252
P
R
T
I
N
I
P
Y
P
K
A
G
A
K
N
Dog
Lupus familis
XP_850205
760
87694
Y252
P
R
T
I
N
I
P
Y
P
K
A
G
A
K
N
Cat
Felis silvestris
Mouse
Mus musculus
P97321
761
87926
Y252
P
R
T
I
N
I
P
Y
P
K
A
G
A
K
N
Rat
Rattus norvegicus
P14740
767
88070
I252
Q
Y
P
K
T
V
W
I
P
Y
P
K
A
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512952
760
87513
Y251
P
R
T
I
N
I
P
Y
P
K
A
G
A
K
N
Chicken
Gallus gallus
NP_001026426
759
86325
I252
Q
Y
P
K
T
I
R
I
P
Y
P
K
A
G
A
Frog
Xenopus laevis
NP_001079272
755
86900
Y249
P
R
T
M
A
I
P
Y
P
K
A
G
M
K
N
Zebra Danio
Brachydanio rerio
XP_001920834
793
90752
Y292
P
V
T
V
F
V
P
Y
P
K
A
G
S
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18253
829
94369
P306
Y
V
E
Y
F
E
L
P
Y
P
K
A
G
V
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P18962
818
93386
S291
D
I
Y
P
E
M
R
S
I
K
Y
P
K
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.2
99.6
93.4
N.A.
89.6
52.7
N.A.
83.9
55.1
58
49.8
N.A.
N.A.
N.A.
28.3
N.A.
Protein Similarity:
100
54.1
99.7
97.5
N.A.
94.4
72.4
N.A.
92.3
72.5
75.2
68.7
N.A.
N.A.
N.A.
44.3
N.A.
P-Site Identity:
100
46.6
100
100
N.A.
100
13.3
N.A.
100
20
80
53.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
60
100
100
N.A.
100
20
N.A.
100
20
86.6
73.3
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
67
9
59
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
9
9
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
67
9
17
9
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
42
0
59
0
17
9
0
0
0
0
0
9
% I
% Lys:
0
0
0
25
0
0
0
0
0
75
9
17
9
50
0
% K
% Leu:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
9
0
9
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
42
0
0
0
0
0
0
0
0
0
59
% N
% Pro:
67
0
17
9
9
0
59
9
84
9
17
9
0
0
0
% P
% Gln:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
50
0
0
0
0
17
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
9
0
0
0
0
17
9
0
% S
% Thr:
0
9
59
0
17
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
17
9
9
0
17
0
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
9
17
9
9
0
9
0
67
9
17
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _