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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAP
All Species:
28.79
Human Site:
Y595
Identified Species:
57.58
UniProt:
Q12884
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12884
NP_004451.2
760
87713
Y595
V
Y
R
K
L
G
V
Y
E
V
E
D
Q
I
T
Chimpanzee
Pan troglodytes
Q5IS50
803
91393
L621
V
R
R
R
L
G
L
L
E
E
K
D
Q
M
E
Rhesus Macaque
Macaca mulatta
XP_001096858
760
87738
Y595
V
Y
R
K
L
G
V
Y
E
V
E
D
Q
I
T
Dog
Lupus familis
XP_850205
760
87694
Y595
V
Y
R
K
L
G
V
Y
E
V
E
D
Q
I
T
Cat
Felis silvestris
Mouse
Mus musculus
P97321
761
87926
Y595
V
Y
R
K
L
G
V
Y
E
V
E
D
Q
L
T
Rat
Rattus norvegicus
P14740
767
88070
L602
I
N
K
R
L
G
T
L
E
V
E
D
Q
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512952
760
87513
Y594
V
Y
R
R
L
G
V
Y
E
T
E
D
Q
I
S
Chicken
Gallus gallus
NP_001026426
759
86325
Y595
I
N
R
R
L
G
T
Y
E
V
E
D
Q
I
S
Frog
Xenopus laevis
NP_001079272
755
86900
V592
I
N
N
R
L
G
T
V
A
V
E
D
Q
I
F
Zebra Danio
Brachydanio rerio
XP_001920834
793
90752
Y630
I
Y
E
R
L
G
T
Y
E
V
E
D
Q
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18253
829
94369
A661
V
Y
R
K
L
G
D
A
E
V
V
D
T
L
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P18962
818
93386
Y650
V
R
D
R
L
G
D
Y
E
A
R
D
Q
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.2
99.6
93.4
N.A.
89.6
52.7
N.A.
83.9
55.1
58
49.8
N.A.
N.A.
N.A.
28.3
N.A.
Protein Similarity:
100
54.1
99.7
97.5
N.A.
94.4
72.4
N.A.
92.3
72.5
75.2
68.7
N.A.
N.A.
N.A.
44.3
N.A.
P-Site Identity:
100
46.6
100
100
N.A.
93.3
53.3
N.A.
80
66.6
46.6
73.3
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
100
73.3
N.A.
93.3
86.6
60
86.6
N.A.
N.A.
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
9
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
17
0
0
0
0
100
0
0
9
% D
% Glu:
0
0
9
0
0
0
0
0
92
9
75
0
0
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
34
0
0
0
0
0
0
0
0
0
0
0
0
75
0
% I
% Lys:
0
0
9
42
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
0
0
0
0
100
0
9
17
0
0
0
0
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
25
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
92
0
0
% Q
% Arg:
0
17
67
59
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% S
% Thr:
0
0
0
0
0
0
34
0
0
9
0
0
9
0
42
% T
% Val:
67
0
0
0
0
0
42
9
0
75
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
59
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _