Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COX10 All Species: 4.24
Human Site: S103 Identified Species: 6.67
UniProt: Q12887 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12887 NP_001294.2 443 48910 S103 I Y E M R P L S P P S L S L S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001114525 443 49311 S103 M Y E M R P L S A P S L S L S
Dog Lupus familis XP_546634 787 85953 P446 I C E M R P L P P P S L P L S
Cat Felis silvestris
Mouse Mus musculus Q8CFY5 443 48865 P103 E D E L P S F P A P S R P L S
Rat Rattus norvegicus XP_001077717 442 48686 P103 V D E L P P F P A P S L P L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509146 496 53440 L159 A P A P A E T L P R A L G P V
Chicken Gallus gallus NP_001025871 448 49551 H102 I T P V S P V H H P P L S E L
Frog Xenopus laevis NP_001090414 419 46090 E90 T F P L P T P E S Y K N A T T
Zebra Danio Brachydanio rerio XP_685590 543 59752 Q196 R D D S M V R Q V Q Q I P A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609382 391 42543 M62 P D S Q I T W M P S P Y T M P
Honey Bee Apis mellifera XP_392628 418 47202 D89 Q K D L C I N D K E E W Q H I
Nematode Worm Caenorhab. elegans NP_496708 397 43594 I68 G K R H K K D I D I I V G D Q
Sea Urchin Strong. purpuratus XP_001193030 440 47997 Q101 E R V E K A I Q S T V D Q V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21592 462 52129 D119 P F N V K L V D P M V R K S K
Red Bread Mold Neurospora crassa Q7S5E7 535 56994 A130 R R Q A Q R K A A A A A A A A
Conservation
Percent
Protein Identity: 100 N.A. 94.8 48.5 N.A. 82.1 81.7 N.A. 63.7 67.8 61.4 51 N.A. 45.8 42.8 40.6 44.4
Protein Similarity: 100 N.A. 96.3 52.2 N.A. 88.7 88.2 N.A. 70.3 79.9 72.9 62.7 N.A. 59.1 58.2 54.6 59.8
P-Site Identity: 100 N.A. 86.6 80 N.A. 33.3 46.6 N.A. 13.3 33.3 0 0 N.A. 6.6 0 0 6.6
P-Site Similarity: 100 N.A. 93.3 80 N.A. 40 60 N.A. 20 46.6 26.6 13.3 N.A. 20 13.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.8 30.4
Protein Similarity: N.A. N.A. N.A. N.A. 48.7 43.9
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 7 7 7 0 7 27 7 14 7 14 14 7 % A
% Cys: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 27 14 0 0 0 7 14 7 0 0 7 0 7 0 % D
% Glu: 14 0 34 7 0 7 0 7 0 7 7 0 0 7 0 % E
% Phe: 0 14 0 0 0 0 14 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % G
% His: 0 0 0 7 0 0 0 7 7 0 0 0 0 7 0 % H
% Ile: 20 0 0 0 7 7 7 7 0 7 7 7 0 0 7 % I
% Lys: 0 14 0 0 20 7 7 0 7 0 7 0 7 0 7 % K
% Leu: 0 0 0 27 0 7 20 7 0 0 0 40 0 34 14 % L
% Met: 7 0 0 20 7 0 0 7 0 7 0 0 0 7 0 % M
% Asn: 0 0 7 0 0 0 7 0 0 0 0 7 0 0 0 % N
% Pro: 14 7 14 7 20 34 7 20 34 40 14 0 27 7 7 % P
% Gln: 7 0 7 7 7 0 0 14 0 7 7 0 14 0 7 % Q
% Arg: 14 14 7 0 20 7 7 0 0 7 0 14 0 0 0 % R
% Ser: 0 0 7 7 7 7 0 14 14 7 34 0 20 7 40 % S
% Thr: 7 7 0 0 0 14 7 0 0 7 0 0 7 7 7 % T
% Val: 7 0 7 14 0 7 14 0 7 0 14 7 0 7 7 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % W
% Tyr: 0 14 0 0 0 0 0 0 0 7 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _