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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX10
All Species:
16.97
Human Site:
S110
Identified Species:
26.67
UniProt:
Q12887
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12887
NP_001294.2
443
48910
S110
S
P
P
S
L
S
L
S
R
K
P
N
E
K
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001114525
443
49311
S110
S
A
P
S
L
S
L
S
R
K
P
N
E
K
E
Dog
Lupus familis
XP_546634
787
85953
S453
P
P
P
S
L
P
L
S
R
K
P
N
E
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFY5
443
48865
S110
P
A
P
S
R
P
L
S
R
K
P
N
E
E
L
Rat
Rattus norvegicus
XP_001077717
442
48686
S110
P
A
P
S
L
P
L
S
Q
K
P
N
E
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509146
496
53440
V166
L
P
R
A
L
G
P
V
A
P
P
C
P
P
A
Chicken
Gallus gallus
NP_001025871
448
49551
L109
H
H
P
P
L
S
E
L
R
E
I
K
P
A
A
Frog
Xenopus laevis
NP_001090414
419
46090
T97
E
S
Y
K
N
A
T
T
Q
G
P
P
A
D
H
Zebra Danio
Brachydanio rerio
XP_685590
543
59752
L203
Q
V
Q
Q
I
P
A
L
K
P
E
P
G
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609382
391
42543
P69
M
P
S
P
Y
T
M
P
G
K
T
L
S
Q
Y
Honey Bee
Apis mellifera
XP_392628
418
47202
I96
D
K
E
E
W
Q
H
I
K
L
D
S
G
K
L
Nematode Worm
Caenorhab. elegans
NP_496708
397
43594
Q75
I
D
I
I
V
G
D
Q
Y
L
Q
Q
W
Y
K
Sea Urchin
Strong. purpuratus
XP_001193030
440
47997
S108
Q
S
T
V
D
Q
V
S
P
C
P
I
E
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21592
462
52129
K126
D
P
M
V
R
K
S
K
R
P
S
H
A
I
S
Red Bread Mold
Neurospora crassa
Q7S5E7
535
56994
A137
A
A
A
A
A
A
A
A
A
A
N
G
E
T
P
Conservation
Percent
Protein Identity:
100
N.A.
94.8
48.5
N.A.
82.1
81.7
N.A.
63.7
67.8
61.4
51
N.A.
45.8
42.8
40.6
44.4
Protein Similarity:
100
N.A.
96.3
52.2
N.A.
88.7
88.2
N.A.
70.3
79.9
72.9
62.7
N.A.
59.1
58.2
54.6
59.8
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
60
60
N.A.
20
26.6
6.6
6.6
N.A.
13.3
6.6
0
20
P-Site Similarity:
100
N.A.
93.3
86.6
N.A.
66.6
66.6
N.A.
26.6
33.3
26.6
20
N.A.
33.3
20
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.8
30.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.7
43.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
27
7
14
7
14
14
7
14
7
0
0
14
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% C
% Asp:
14
7
0
0
7
0
7
0
0
0
7
0
0
7
0
% D
% Glu:
7
0
7
7
0
0
7
0
0
7
7
0
47
7
27
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
14
0
0
7
7
0
7
14
0
0
% G
% His:
7
7
0
0
0
0
7
0
0
0
0
7
0
0
7
% H
% Ile:
7
0
7
7
7
0
0
7
0
0
7
7
0
7
0
% I
% Lys:
0
7
0
7
0
7
0
7
14
40
0
7
0
27
14
% K
% Leu:
7
0
0
0
40
0
34
14
0
14
0
7
0
7
14
% L
% Met:
7
0
7
0
0
0
7
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
7
34
0
0
0
% N
% Pro:
20
34
40
14
0
27
7
7
7
20
54
14
14
14
7
% P
% Gln:
14
0
7
7
0
14
0
7
14
0
7
7
0
7
0
% Q
% Arg:
0
0
7
0
14
0
0
0
40
0
0
0
0
0
0
% R
% Ser:
14
14
7
34
0
20
7
40
0
0
7
7
7
0
7
% S
% Thr:
0
0
7
0
0
7
7
7
0
0
7
0
0
14
0
% T
% Val:
0
7
0
14
7
0
7
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
7
0
7
0
0
0
7
0
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _