KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX10
All Species:
10
Human Site:
S130
Identified Species:
15.71
UniProt:
Q12887
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12887
NP_001294.2
443
48910
S130
P
D
S
V
I
E
D
S
I
D
V
G
K
E
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001114525
443
49311
S130
P
A
S
V
I
E
D
S
I
D
V
R
K
E
T
Dog
Lupus familis
XP_546634
787
85953
S473
S
A
S
I
I
E
G
S
L
D
A
G
K
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFY5
443
48865
L130
T
S
I
V
D
H
S
L
D
T
A
K
E
K
K
Rat
Rattus norvegicus
XP_001077717
442
48686
D130
S
I
V
D
H
S
L
D
T
A
K
E
Q
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509146
496
53440
A186
G
A
E
G
S
E
A
A
S
P
A
G
P
A
L
Chicken
Gallus gallus
NP_001025871
448
49551
S129
A
R
P
P
T
A
E
S
K
E
E
R
Q
W
R
Frog
Xenopus laevis
NP_001090414
419
46090
R117
A
N
E
E
R
G
W
R
E
M
K
V
E
I
S
Zebra Danio
Brachydanio rerio
XP_685590
543
59752
P223
T
E
S
N
Q
V
E
P
E
A
D
R
V
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609382
391
42543
V89
F
R
L
T
S
L
V
V
I
T
T
M
G
G
Y
Honey Bee
Apis mellifera
XP_392628
418
47202
T116
M
L
S
K
I
R
L
T
S
L
V
V
I
T
T
Nematode Worm
Caenorhab. elegans
NP_496708
397
43594
L95
L
A
A
D
Y
L
A
L
C
K
S
K
L
S
L
Sea Urchin
Strong. purpuratus
XP_001193030
440
47997
E128
E
G
I
E
V
G
V
E
E
E
V
R
W
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21592
462
52129
I146
K
T
L
K
K
K
V
I
M
P
Y
L
Q
L
T
Red Bread Mold
Neurospora crassa
Q7S5E7
535
56994
L157
P
D
A
P
T
A
D
L
A
P
D
A
S
S
Q
Conservation
Percent
Protein Identity:
100
N.A.
94.8
48.5
N.A.
82.1
81.7
N.A.
63.7
67.8
61.4
51
N.A.
45.8
42.8
40.6
44.4
Protein Similarity:
100
N.A.
96.3
52.2
N.A.
88.7
88.2
N.A.
70.3
79.9
72.9
62.7
N.A.
59.1
58.2
54.6
59.8
P-Site Identity:
100
N.A.
86.6
60
N.A.
6.6
0
N.A.
13.3
6.6
0
6.6
N.A.
6.6
26.6
0
6.6
P-Site Similarity:
100
N.A.
86.6
73.3
N.A.
20
13.3
N.A.
20
26.6
20
20
N.A.
6.6
33.3
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.8
30.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.7
43.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
27
14
0
0
14
14
7
7
14
20
7
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
14
0
14
7
0
20
7
7
20
14
0
0
0
0
% D
% Glu:
7
7
14
14
0
27
14
7
20
14
7
7
14
20
14
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
0
7
0
14
7
0
0
0
0
20
7
7
0
% G
% His:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
14
7
27
0
0
7
20
0
0
0
7
7
0
% I
% Lys:
7
0
0
14
7
7
0
0
7
7
14
14
20
14
7
% K
% Leu:
7
7
14
0
0
14
14
20
7
7
0
7
7
7
14
% L
% Met:
7
0
0
0
0
0
0
0
7
7
0
7
0
0
0
% M
% Asn:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
20
0
7
14
0
0
0
7
0
20
0
0
7
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
20
0
7
% Q
% Arg:
0
14
0
0
7
7
0
7
0
0
0
27
0
7
14
% R
% Ser:
14
7
34
0
14
7
7
27
14
0
7
0
7
14
7
% S
% Thr:
14
7
0
7
14
0
0
7
7
14
7
0
0
7
34
% T
% Val:
0
0
7
20
7
7
20
7
0
0
27
14
7
0
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
7
7
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _