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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX10
All Species:
32.42
Human Site:
S281
Identified Species:
50.95
UniProt:
Q12887
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12887
NP_001294.2
443
48910
S281
Y
T
P
L
K
R
I
S
I
A
N
T
W
V
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001114525
443
49311
S281
Y
T
P
L
K
R
I
S
I
V
N
T
W
V
G
Dog
Lupus familis
XP_546634
787
85953
S624
Y
T
P
L
K
R
I
S
I
A
N
T
W
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFY5
443
48865
S280
Y
T
P
L
K
R
V
S
I
T
N
T
W
V
G
Rat
Rattus norvegicus
XP_001077717
442
48686
S279
Y
T
P
L
K
R
V
S
I
A
N
T
W
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509146
496
53440
S337
Y
T
P
L
K
R
I
S
I
A
N
T
W
V
G
Chicken
Gallus gallus
NP_001025871
448
49551
T277
K
R
M
S
I
A
N
T
W
V
G
A
V
V
G
Frog
Xenopus laevis
NP_001090414
419
46090
V264
N
T
W
V
G
A
V
V
G
A
L
P
P
V
M
Zebra Danio
Brachydanio rerio
XP_685590
543
59752
S374
Y
T
P
L
K
R
L
S
I
A
N
T
W
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609382
391
42543
V236
G
A
M
I
L
A
G
V
L
Y
A
W
Q
F
P
Honey Bee
Apis mellifera
XP_392628
418
47202
W263
D
I
V
S
P
G
A
W
I
M
S
G
I
L
Y
Nematode Worm
Caenorhab. elegans
NP_496708
397
43594
L242
Y
A
A
A
T
G
Y
L
D
P
A
A
W
C
L
Sea Urchin
Strong. purpuratus
XP_001193030
440
47997
T275
K
R
Y
S
I
V
N
T
W
V
G
A
V
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21592
462
52129
P297
M
G
W
A
A
A
S
P
L
S
H
P
G
S
W
Red Bread Mold
Neurospora crassa
Q7S5E7
535
56994
S323
Y
T
P
L
K
R
I
S
A
V
N
T
W
V
G
Conservation
Percent
Protein Identity:
100
N.A.
94.8
48.5
N.A.
82.1
81.7
N.A.
63.7
67.8
61.4
51
N.A.
45.8
42.8
40.6
44.4
Protein Similarity:
100
N.A.
96.3
52.2
N.A.
88.7
88.2
N.A.
70.3
79.9
72.9
62.7
N.A.
59.1
58.2
54.6
59.8
P-Site Identity:
100
N.A.
93.3
100
N.A.
86.6
93.3
N.A.
100
13.3
20
93.3
N.A.
0
6.6
13.3
13.3
P-Site Similarity:
100
N.A.
93.3
100
N.A.
93.3
100
N.A.
100
20
33.3
100
N.A.
13.3
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.8
30.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.7
43.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
86.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
7
14
7
27
7
0
7
40
14
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
7
7
0
0
7
14
7
0
7
0
14
7
7
0
67
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
7
0
7
14
0
34
0
54
0
0
0
7
0
0
% I
% Lys:
14
0
0
0
54
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
54
7
0
7
7
14
0
7
0
0
7
7
% L
% Met:
7
0
14
0
0
0
0
0
0
7
0
0
0
0
7
% M
% Asn:
7
0
0
0
0
0
14
0
0
0
54
0
0
0
0
% N
% Pro:
0
0
54
0
7
0
0
7
0
7
0
14
7
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
14
0
0
0
54
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
20
0
0
7
54
0
7
7
0
0
7
0
% S
% Thr:
0
60
0
0
7
0
0
14
0
7
0
54
0
0
0
% T
% Val:
0
0
7
7
0
7
20
14
0
27
0
0
14
74
0
% V
% Trp:
0
0
14
0
0
0
0
7
14
0
0
7
60
0
7
% W
% Tyr:
60
0
7
0
0
0
7
0
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _