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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX10
All Species:
27.88
Human Site:
S407
Identified Species:
43.81
UniProt:
Q12887
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12887
NP_001294.2
443
48910
S407
Y
V
D
A
D
R
R
S
S
R
R
L
F
F
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001114525
443
49311
S407
Y
V
D
A
D
R
R
S
S
R
R
L
F
F
C
Dog
Lupus familis
XP_546634
787
85953
S750
Y
T
D
A
D
R
K
S
S
R
K
L
F
F
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFY5
443
48865
S406
Y
V
D
A
D
R
R
S
S
R
K
L
F
F
C
Rat
Rattus norvegicus
XP_001077717
442
48686
S405
Y
V
D
A
D
R
K
S
S
R
K
L
F
F
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509146
496
53440
D460
F
R
F
Y
R
Q
A
D
R
G
S
S
R
R
L
Chicken
Gallus gallus
NP_001025871
448
49551
S399
Y
R
D
A
D
R
S
S
S
R
K
L
F
F
C
Frog
Xenopus laevis
NP_001090414
419
46090
L384
D
R
S
S
S
R
K
L
F
F
C
S
L
W
H
Zebra Danio
Brachydanio rerio
XP_685590
543
59752
N500
Y
R
H
G
D
R
Q
N
S
R
K
L
F
F
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609382
391
42543
K356
K
K
E
W
Y
F
S
K
P
A
G
E
E
N
K
Honey Bee
Apis mellifera
XP_392628
418
47202
Y383
L
I
L
V
N
K
K
Y
W
Y
N
E
K
K
Q
Nematode Worm
Caenorhab. elegans
NP_496708
397
43594
M362
L
P
L
V
M
L
L
M
G
I
S
N
Y
G
R
Sea Urchin
Strong. purpuratus
XP_001193030
440
47997
S397
Y
R
D
A
D
S
K
S
A
R
Q
L
F
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21592
462
52129
Y420
G
L
S
V
A
N
I
Y
A
R
K
T
F
M
A
Red Bread Mold
Neurospora crassa
Q7S5E7
535
56994
G466
W
R
L
E
G
H
K
G
S
A
R
G
L
F
W
Conservation
Percent
Protein Identity:
100
N.A.
94.8
48.5
N.A.
82.1
81.7
N.A.
63.7
67.8
61.4
51
N.A.
45.8
42.8
40.6
44.4
Protein Similarity:
100
N.A.
96.3
52.2
N.A.
88.7
88.2
N.A.
70.3
79.9
72.9
62.7
N.A.
59.1
58.2
54.6
59.8
P-Site Identity:
100
N.A.
100
80
N.A.
93.3
86.6
N.A.
0
80
6.6
60
N.A.
0
0
0
53.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
13.3
86.6
26.6
80
N.A.
6.6
26.6
6.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.8
30.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.7
43.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
47
7
0
7
0
14
14
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
47
% C
% Asp:
7
0
47
0
54
0
0
7
0
0
0
0
0
0
0
% D
% Glu:
0
0
7
7
0
0
0
0
0
0
0
14
7
0
0
% E
% Phe:
7
0
7
0
0
7
0
0
7
7
0
0
60
54
7
% F
% Gly:
7
0
0
7
7
0
0
7
7
7
7
7
0
7
0
% G
% His:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
7
0
0
0
0
7
0
0
7
0
0
0
0
0
% I
% Lys:
7
7
0
0
0
7
40
7
0
0
40
0
7
14
7
% K
% Leu:
14
7
20
0
0
7
7
7
0
0
0
54
14
0
7
% L
% Met:
0
0
0
0
7
0
0
7
0
0
0
0
0
7
0
% M
% Asn:
0
0
0
0
7
7
0
7
0
0
7
7
0
7
0
% N
% Pro:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
7
0
0
0
7
0
0
0
7
% Q
% Arg:
0
40
0
0
7
54
20
0
7
60
20
0
7
7
7
% R
% Ser:
0
0
14
7
7
7
14
47
54
0
14
14
0
0
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
27
0
20
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
7
0
0
7
0
0
0
0
7
0
0
0
0
7
7
% W
% Tyr:
54
0
0
7
7
0
0
14
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _