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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COX10 All Species: 27.27
Human Site: Y342 Identified Species: 42.86
UniProt: Q12887 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12887 NP_001294.2 443 48910 Y342 E D Y S R G G Y C M M S V T H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001114525 443 49311 Y342 E D Y S R G G Y C M M S V T H
Dog Lupus familis XP_546634 787 85953 Y685 E D Y S R G G Y C M M S V T H
Cat Felis silvestris
Mouse Mus musculus Q8CFY5 443 48865 Y341 E D Y S R G G Y C M M S V T H
Rat Rattus norvegicus XP_001077717 442 48686 Y340 E D Y S R G G Y C M M S V T H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509146 496 53440 Y398 E D Y S R G G Y R M M S V T H
Chicken Gallus gallus NP_001025871 448 49551 V339 G G Y C M M S V T H P E L C R
Frog Xenopus laevis NP_001090414 419 46090 L324 M M S V T H P L M C R Q V A L
Zebra Danio Brachydanio rerio XP_685590 543 59752 Y435 E D Y S R G G Y R M M S V T H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609382 391 42543 T296 M A P V L D V T N Y W F A L E
Honey Bee Apis mellifera XP_392628 418 47202 P323 T G L C Y L A P V F N V T N W
Nematode Worm Caenorhab. elegans NP_496708 397 43594 L302 H S V A L L G L C S I A A P L
Sea Urchin Strong. purpuratus XP_001193030 440 47997 T337 G G Y R M M A T T D P G L C R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21592 462 52129 C360 S I L M F P L C F G L S Y F N
Red Bread Mold Neurospora crassa Q7S5E7 535 56994 L401 H E Y K A A G L R M L A W T N
Conservation
Percent
Protein Identity: 100 N.A. 94.8 48.5 N.A. 82.1 81.7 N.A. 63.7 67.8 61.4 51 N.A. 45.8 42.8 40.6 44.4
Protein Similarity: 100 N.A. 96.3 52.2 N.A. 88.7 88.2 N.A. 70.3 79.9 72.9 62.7 N.A. 59.1 58.2 54.6 59.8
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 93.3 6.6 6.6 93.3 N.A. 0 0 13.3 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 93.3 13.3 6.6 93.3 N.A. 0 0 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.8 30.4
Protein Similarity: N.A. N.A. N.A. N.A. 48.7 43.9
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 7 7 14 0 0 0 0 14 14 7 0 % A
% Cys: 0 0 0 14 0 0 0 7 40 7 0 0 0 14 0 % C
% Asp: 0 47 0 0 0 7 0 0 0 7 0 0 0 0 0 % D
% Glu: 47 7 0 0 0 0 0 0 0 0 0 7 0 0 7 % E
% Phe: 0 0 0 0 7 0 0 0 7 7 0 7 0 7 0 % F
% Gly: 14 20 0 0 0 47 60 0 0 7 0 7 0 0 0 % G
% His: 14 0 0 0 0 7 0 0 0 7 0 0 0 0 47 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 14 0 14 14 7 20 0 0 14 0 14 7 14 % L
% Met: 14 7 0 7 14 14 0 0 7 54 47 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 0 7 0 0 7 14 % N
% Pro: 0 0 7 0 0 7 7 7 0 0 14 0 0 7 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Q
% Arg: 0 0 0 7 47 0 0 0 20 0 7 0 0 0 14 % R
% Ser: 7 7 7 47 0 0 7 0 0 7 0 54 0 0 0 % S
% Thr: 7 0 0 0 7 0 0 14 14 0 0 0 7 54 0 % T
% Val: 0 0 7 14 0 0 7 7 7 0 0 7 54 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 7 % W
% Tyr: 0 0 67 0 7 0 0 47 0 7 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _