KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYAL2
All Species:
26.97
Human Site:
S261
Identified Species:
65.93
UniProt:
Q12891
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12891
NP_003764.3
473
53844
S261
L
D
E
T
L
A
S
S
R
H
G
R
N
F
V
Chimpanzee
Pan troglodytes
XP_001168504
473
53826
S261
L
D
E
T
L
A
S
S
R
H
G
R
N
F
V
Rhesus Macaque
Macaca mulatta
XP_001101134
473
53962
S261
L
D
E
T
L
A
S
S
R
H
G
R
N
F
V
Dog
Lupus familis
XP_541876
472
53416
S260
L
D
E
T
L
A
S
S
T
H
G
R
N
F
V
Cat
Felis silvestris
Mouse
Mus musculus
O35632
473
53599
S261
L
D
E
T
L
A
S
S
V
H
S
R
N
F
V
Rat
Rattus norvegicus
Q9Z2Q3
473
53981
S261
L
D
K
T
L
A
S
S
K
H
S
R
N
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507872
472
54425
S250
L
P
E
I
L
K
S
S
T
N
V
L
K
F
V
Chicken
Gallus gallus
XP_414258
478
54697
T270
L
D
P
L
L
A
S
T
P
N
S
R
K
F
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687640
502
57507
N291
M
G
K
I
L
K
D
N
P
K
G
R
Q
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Q08169
382
44241
R180
H
P
F
W
D
D
Q
R
V
E
Q
E
A
K
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.3
89
N.A.
82.2
81.6
N.A.
42.4
55.4
N.A.
45.2
N.A.
N.A.
26.4
N.A.
N.A.
Protein Similarity:
100
100
98.5
92.8
N.A.
90
89
N.A.
61
69.4
N.A.
63.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
46.6
53.3
N.A.
33.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
53.3
66.6
N.A.
53.3
N.A.
N.A.
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
70
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
0
0
10
10
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
60
0
0
0
0
0
0
10
0
10
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
90
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
50
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% H
% Ile:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
20
0
0
20
0
0
10
10
0
0
20
10
0
% K
% Leu:
80
0
0
10
90
0
0
0
0
0
0
10
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
20
0
0
60
0
0
% N
% Pro:
0
20
10
0
0
0
0
0
20
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
10
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
30
0
0
80
0
0
10
% R
% Ser:
0
0
0
0
0
0
80
70
0
0
30
0
0
0
0
% S
% Thr:
0
0
0
60
0
0
0
10
20
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
20
0
10
0
0
0
90
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _