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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM115 All Species: 34.55
Human Site: S267 Identified Species: 58.46
UniProt: Q12893 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12893 NP_008955.1 351 38197 S267 Y D V G A P S S I T I S L P G
Chimpanzee Pan troglodytes XP_516482 351 38195 S267 Y D V G A P S S I T I S L P G
Rhesus Macaque Macaca mulatta XP_001099836 351 38124 S267 Y D V G A P S S I T I S L P G
Dog Lupus familis XP_850145 351 38143 S267 Y D V G A P S S I T I S L P G
Cat Felis silvestris
Mouse Mus musculus Q9WUH1 350 38080 S267 Y D V G A P S S I T I S L P G
Rat Rattus norvegicus NP_001102249 350 38035 S267 Y D V G A P S S I T I S L P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518365 293 32065 H222 G R G D M S D H F A F A T F F
Chicken Gallus gallus
Frog Xenopus laevis NP_001121236 343 37440 S265 Y D V G A P S S I T I S L P G
Zebra Danio Brachydanio rerio NP_001028917 361 39298 S269 Y D V G A P S S I T I S L P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609033 450 49667 S277 I S T A S L T S V S V Q M P G
Honey Bee Apis mellifera XP_392569 362 40565 P277 F D M S N A P P G L I I N L P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782612 199 21894 P127 I S L P G T D P A D A E R R R
Poplar Tree Populus trichocarpa XP_002311100 275 30696 R204 I Y L R Y F Q R K P E T K L R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_566326 304 34065 L233 P V I D P I A L I F H R M L C
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 99.1 96.8 N.A. 94.3 95.7 N.A. 68.9 N.A. 53.5 65.9 N.A. 32.6 40.8 N.A. 32.1
Protein Similarity: 100 99.7 99.4 98 N.A. 95.7 97.4 N.A. 75.7 N.A. 68.9 77.8 N.A. 46.8 59.3 N.A. 41.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 N.A. 100 100 N.A. 20 13.3 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 N.A. 100 100 N.A. 60 26.6 N.A. 6.6
Percent
Protein Identity: 28.2 N.A. N.A. 29.9 N.A. N.A.
Protein Similarity: 44.4 N.A. N.A. 45.8 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 58 8 8 0 8 8 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 65 0 15 0 0 15 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % E
% Phe: 8 0 0 0 0 8 0 0 8 8 8 0 0 8 8 % F
% Gly: 8 0 8 58 8 0 0 0 8 0 0 0 0 0 65 % G
% His: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % H
% Ile: 22 0 8 0 0 8 0 0 65 0 65 8 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % K
% Leu: 0 0 15 0 0 8 0 8 0 8 0 0 58 22 0 % L
% Met: 0 0 8 0 8 0 0 0 0 0 0 0 15 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 8 0 0 8 8 58 8 15 0 8 0 0 0 65 8 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % Q
% Arg: 0 8 0 8 0 0 0 8 0 0 0 8 8 8 15 % R
% Ser: 0 15 0 8 8 8 58 65 0 8 0 58 0 0 0 % S
% Thr: 0 0 8 0 0 8 8 0 0 58 0 8 8 0 0 % T
% Val: 0 8 58 0 0 0 0 0 8 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 58 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _