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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM115
All Species:
20.3
Human Site:
S324
Identified Species:
34.36
UniProt:
Q12893
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12893
NP_008955.1
351
38197
S324
K
V
D
S
P
L
P
S
D
K
A
P
T
P
P
Chimpanzee
Pan troglodytes
XP_516482
351
38195
S324
K
L
D
S
P
L
P
S
D
K
A
P
T
P
P
Rhesus Macaque
Macaca mulatta
XP_001099836
351
38124
S324
K
V
D
S
P
L
P
S
D
K
A
P
T
P
P
Dog
Lupus familis
XP_850145
351
38143
S324
K
V
D
S
P
L
P
S
D
K
A
P
T
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUH1
350
38080
L324
K
T
D
S
P
L
P
L
E
E
A
S
T
P
P
Rat
Rattus norvegicus
NP_001102249
350
38035
S324
K
T
D
S
P
L
P
S
E
Q
A
S
T
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518365
293
32065
S267
R
Y
D
V
G
A
P
S
S
I
T
I
S
L
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121236
343
37440
I317
E
E
E
D
G
N
E
I
D
S
S
F
H
S
G
Zebra Danio
Brachydanio rerio
NP_001028917
361
39298
L326
E
V
R
T
D
T
P
L
L
S
S
R
E
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609033
450
49667
I408
S
T
M
S
P
I
A
I
P
M
P
A
P
P
P
Honey Bee
Apis mellifera
XP_392569
362
40565
A328
K
H
S
P
V
P
P
A
V
S
I
P
I
P
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782612
199
21894
S173
P
A
S
P
A
P
S
S
V
S
L
M
S
D
A
Poplar Tree
Populus trichocarpa
XP_002311100
275
30696
T249
M
L
C
G
R
F
E
T
S
T
E
A
H
G
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_566326
304
34065
L278
R
E
R
G
A
R
A
L
E
E
R
L
G
T
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
99.1
96.8
N.A.
94.3
95.7
N.A.
68.9
N.A.
53.5
65.9
N.A.
32.6
40.8
N.A.
32.1
Protein Similarity:
100
99.7
99.4
98
N.A.
95.7
97.4
N.A.
75.7
N.A.
68.9
77.8
N.A.
46.8
59.3
N.A.
41.3
P-Site Identity:
100
93.3
100
93.3
N.A.
66.6
73.3
N.A.
26.6
N.A.
6.6
13.3
N.A.
26.6
26.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
80
86.6
N.A.
40
N.A.
26.6
33.3
N.A.
33.3
33.3
N.A.
13.3
Percent
Protein Identity:
28.2
N.A.
N.A.
29.9
N.A.
N.A.
Protein Similarity:
44.4
N.A.
N.A.
45.8
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
15
8
15
8
0
0
43
15
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
8
8
0
0
0
36
0
0
0
0
8
15
% D
% Glu:
15
15
8
0
0
0
15
0
22
15
8
0
8
0
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
15
15
0
0
0
0
0
0
0
8
8
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
15
0
0
% H
% Ile:
0
0
0
0
0
8
0
15
0
8
8
8
8
0
0
% I
% Lys:
50
0
0
0
0
0
0
0
0
29
0
0
0
0
0
% K
% Leu:
0
15
0
0
0
43
0
22
8
0
8
8
0
15
0
% L
% Met:
8
0
8
0
0
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
15
50
15
65
0
8
0
8
36
8
50
58
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
15
0
15
0
8
8
0
0
0
0
8
8
0
0
0
% R
% Ser:
8
0
15
50
0
0
8
50
15
29
15
15
15
8
8
% S
% Thr:
0
22
0
8
0
8
0
8
0
8
8
0
43
15
0
% T
% Val:
0
29
0
8
8
0
0
0
15
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _