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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM115
All Species:
24.85
Human Site:
T256
Identified Species:
42.05
UniProt:
Q12893
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12893
NP_008955.1
351
38197
T256
K
V
K
I
C
Q
K
T
V
K
R
Y
D
V
G
Chimpanzee
Pan troglodytes
XP_516482
351
38195
T256
K
V
K
I
C
Q
K
T
V
K
R
Y
D
V
G
Rhesus Macaque
Macaca mulatta
XP_001099836
351
38124
T256
K
V
K
I
C
Q
K
T
V
K
R
Y
D
V
G
Dog
Lupus familis
XP_850145
351
38143
T256
K
V
K
I
C
Q
K
T
V
K
R
Y
D
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUH1
350
38080
T256
K
V
K
I
C
Q
K
T
V
K
R
Y
D
V
G
Rat
Rattus norvegicus
NP_001102249
350
38035
T256
K
V
K
I
C
Q
K
T
V
K
R
Y
D
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518365
293
32065
R211
I
Y
L
R
F
Y
Q
R
H
S
R
G
R
G
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121236
343
37440
A254
K
L
H
L
C
S
Q
A
V
R
R
Y
D
V
G
Zebra Danio
Brachydanio rerio
NP_001028917
361
39298
M258
K
I
K
I
C
R
K
M
V
K
R
Y
D
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609033
450
49667
P266
G
V
V
K
T
P
T
P
L
R
T
I
S
T
A
Honey Bee
Apis mellifera
XP_392569
362
40565
V266
R
V
G
I
C
R
K
V
V
R
R
F
D
M
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782612
199
21894
S116
K
Y
D
V
G
A
P
S
P
I
T
I
S
L
P
Poplar Tree
Populus trichocarpa
XP_002311100
275
30696
Y193
P
T
L
I
F
G
T
Y
M
S
W
I
Y
L
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_566326
304
34065
E222
A
F
S
T
F
F
P
E
L
L
R
P
V
I
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
99.1
96.8
N.A.
94.3
95.7
N.A.
68.9
N.A.
53.5
65.9
N.A.
32.6
40.8
N.A.
32.1
Protein Similarity:
100
99.7
99.4
98
N.A.
95.7
97.4
N.A.
75.7
N.A.
68.9
77.8
N.A.
46.8
59.3
N.A.
41.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
N.A.
53.3
80
N.A.
6.6
46.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
N.A.
80
93.3
N.A.
20
80
N.A.
26.6
Percent
Protein Identity:
28.2
N.A.
N.A.
29.9
N.A.
N.A.
Protein Similarity:
44.4
N.A.
N.A.
45.8
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
65
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
65
0
15
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
22
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
8
0
8
8
0
0
0
0
0
8
0
8
58
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
8
0
65
0
0
0
0
0
8
0
22
0
8
0
% I
% Lys:
65
0
50
8
0
0
58
0
0
50
0
0
0
0
0
% K
% Leu:
0
8
15
8
0
0
0
0
15
8
0
0
0
15
0
% L
% Met:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
8
15
8
8
0
0
8
0
0
8
% P
% Gln:
0
0
0
0
0
43
15
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
8
0
15
0
8
0
22
79
0
8
0
8
% R
% Ser:
0
0
8
0
0
8
0
8
0
15
0
0
15
0
8
% S
% Thr:
0
8
0
8
8
0
15
43
0
0
15
0
0
8
0
% T
% Val:
0
58
8
8
0
0
0
8
65
0
0
0
8
58
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
15
0
0
0
8
0
8
0
0
0
58
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _