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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM115
All Species:
31.82
Human Site:
T275
Identified Species:
53.85
UniProt:
Q12893
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12893
NP_008955.1
351
38197
T275
I
T
I
S
L
P
G
T
D
P
Q
D
A
E
R
Chimpanzee
Pan troglodytes
XP_516482
351
38195
T275
I
T
I
S
L
P
G
T
D
P
Q
D
A
E
R
Rhesus Macaque
Macaca mulatta
XP_001099836
351
38124
T275
I
T
I
S
L
P
G
T
D
P
Q
D
A
E
R
Dog
Lupus familis
XP_850145
351
38143
T275
I
T
I
S
L
P
G
T
D
P
Q
D
A
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUH1
350
38080
T275
I
T
I
S
L
P
G
T
D
P
Q
D
A
E
R
Rat
Rattus norvegicus
NP_001102249
350
38035
T275
I
T
I
S
L
P
G
T
D
P
Q
D
A
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518365
293
32065
P230
F
A
F
A
T
F
F
P
E
I
L
Q
P
V
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121236
343
37440
T273
I
T
I
S
L
P
G
T
D
P
Q
D
A
E
R
Zebra Danio
Brachydanio rerio
NP_001028917
361
39298
T277
I
T
I
S
L
P
G
T
D
P
Q
D
A
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609033
450
49667
V285
V
S
V
Q
M
P
G
V
D
P
H
D
I
E
R
Honey Bee
Apis mellifera
XP_392569
362
40565
G285
G
L
I
I
N
L
P
G
I
D
P
H
D
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782612
199
21894
Q135
A
D
A
E
R
R
R
Q
I
A
L
K
A
L
N
Poplar Tree
Populus trichocarpa
XP_002311100
275
30696
G212
K
P
E
T
K
L
R
G
D
P
S
D
D
F
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_566326
304
34065
G241
I
F
H
R
M
L
C
G
R
S
N
A
T
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
99.1
96.8
N.A.
94.3
95.7
N.A.
68.9
N.A.
53.5
65.9
N.A.
32.6
40.8
N.A.
32.1
Protein Similarity:
100
99.7
99.4
98
N.A.
95.7
97.4
N.A.
75.7
N.A.
68.9
77.8
N.A.
46.8
59.3
N.A.
41.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
N.A.
100
100
N.A.
46.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
N.A.
100
100
N.A.
73.3
6.6
N.A.
6.6
Percent
Protein Identity:
28.2
N.A.
N.A.
29.9
N.A.
N.A.
Protein Similarity:
44.4
N.A.
N.A.
45.8
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
0
0
0
0
8
0
8
65
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
72
8
0
72
15
0
0
% D
% Glu:
0
0
8
8
0
0
0
0
8
0
0
0
0
65
15
% E
% Phe:
8
8
8
0
0
8
8
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
0
0
0
0
65
22
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
65
0
65
8
0
0
0
0
15
8
0
0
8
0
0
% I
% Lys:
8
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
8
0
0
58
22
0
0
0
0
15
0
0
8
0
% L
% Met:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
8
% N
% Pro:
0
8
0
0
0
65
8
8
0
72
8
0
8
0
0
% P
% Gln:
0
0
0
8
0
0
0
8
0
0
58
8
0
0
0
% Q
% Arg:
0
0
0
8
8
8
15
0
8
0
0
0
0
0
65
% R
% Ser:
0
8
0
58
0
0
0
0
0
8
8
0
0
15
0
% S
% Thr:
0
58
0
8
8
0
0
58
0
0
0
0
8
0
0
% T
% Val:
8
0
8
0
0
0
0
8
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _