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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM115
All Species:
34.85
Human Site:
Y208
Identified Species:
58.97
UniProt:
Q12893
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12893
NP_008955.1
351
38197
Y208
S
W
V
Y
L
R
F
Y
Q
R
H
S
R
G
R
Chimpanzee
Pan troglodytes
XP_516482
351
38195
Y208
S
W
V
Y
L
R
F
Y
Q
R
H
S
R
G
R
Rhesus Macaque
Macaca mulatta
XP_001099836
351
38124
Y208
S
W
V
Y
L
R
F
Y
Q
R
H
S
R
G
R
Dog
Lupus familis
XP_850145
351
38143
Y208
S
W
V
Y
L
R
F
Y
Q
R
H
S
R
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUH1
350
38080
Y208
S
W
V
Y
L
R
F
Y
Q
R
H
S
R
G
R
Rat
Rattus norvegicus
NP_001102249
350
38035
Y208
S
W
V
Y
L
R
F
Y
Q
R
H
S
R
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518365
293
32065
M167
L
K
V
P
Q
V
R
M
K
V
V
P
M
L
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121236
343
37440
Y206
G
W
V
Y
L
R
F
Y
Q
R
H
S
R
G
R
Zebra Danio
Brachydanio rerio
NP_001028917
361
39298
Y210
G
W
V
Y
L
R
F
Y
Q
R
H
S
R
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609033
450
49667
Y216
S
W
I
Y
L
R
F
Y
Q
H
H
P
N
G
R
Honey Bee
Apis mellifera
XP_392569
362
40565
Q218
W
T
Y
L
R
F
Y
Q
K
H
N
N
G
T
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782612
199
21894
F72
R
G
D
M
A
D
T
F
S
F
A
S
F
F
P
Poplar Tree
Populus trichocarpa
XP_002311100
275
30696
P149
V
G
I
K
Q
I
I
P
D
Q
E
L
S
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_566326
304
34065
A178
S
F
F
T
L
D
S
A
A
Y
L
P
T
L
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
99.1
96.8
N.A.
94.3
95.7
N.A.
68.9
N.A.
53.5
65.9
N.A.
32.6
40.8
N.A.
32.1
Protein Similarity:
100
99.7
99.4
98
N.A.
95.7
97.4
N.A.
75.7
N.A.
68.9
77.8
N.A.
46.8
59.3
N.A.
41.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
N.A.
93.3
93.3
N.A.
73.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
N.A.
93.3
93.3
N.A.
80
33.3
N.A.
13.3
Percent
Protein Identity:
28.2
N.A.
N.A.
29.9
N.A.
N.A.
Protein Similarity:
44.4
N.A.
N.A.
45.8
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
15
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
8
8
0
0
8
65
8
0
8
0
0
8
8
0
% F
% Gly:
15
15
0
0
0
0
0
0
0
0
0
0
8
65
0
% G
% His:
0
0
0
0
0
0
0
0
0
15
65
0
0
0
0
% H
% Ile:
0
0
15
0
0
8
8
0
0
0
0
0
0
0
8
% I
% Lys:
0
8
0
8
0
0
0
0
15
0
0
0
0
0
0
% K
% Leu:
8
0
0
8
72
0
0
0
0
0
8
8
0
22
15
% L
% Met:
0
0
0
8
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
8
8
0
0
% N
% Pro:
0
0
0
8
0
0
0
8
0
0
0
22
0
0
8
% P
% Gln:
0
0
0
0
15
0
0
8
65
8
0
0
0
0
0
% Q
% Arg:
8
0
0
0
8
65
8
0
0
58
0
0
58
0
72
% R
% Ser:
58
0
0
0
0
0
8
0
8
0
0
65
8
0
0
% S
% Thr:
0
8
0
8
0
0
8
0
0
0
0
0
8
8
0
% T
% Val:
8
0
65
0
0
8
0
0
0
8
8
0
0
0
0
% V
% Trp:
8
65
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
65
0
0
8
65
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _