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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IFRD2
All Species:
23.33
Human Site:
S270
Identified Species:
51.33
UniProt:
Q12894
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12894
NP_006755.4
442
48048
S270
P
R
L
P
Q
L
L
S
S
E
S
V
N
L
R
Chimpanzee
Pan troglodytes
XP_001167735
607
65633
S436
R
L
P
Q
L
L
S
S
E
S
V
N
L
R
I
Rhesus Macaque
Macaca mulatta
XP_001099740
451
50204
S276
H
K
L
P
S
L
L
S
C
D
D
V
N
M
R
Dog
Lupus familis
XP_541877
441
47736
S269
P
R
L
P
Q
L
L
S
S
E
S
V
N
L
R
Cat
Felis silvestris
Mouse
Mus musculus
P19182
449
49925
S274
H
K
L
P
S
L
L
S
C
D
D
V
N
M
R
Rat
Rattus norvegicus
P20695
449
49764
S274
H
K
L
P
S
L
L
S
C
D
D
V
N
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508967
464
50902
S292
A
Q
L
P
R
L
L
S
S
D
N
V
H
L
R
Chicken
Gallus gallus
NP_001001468
434
48793
C260
K
L
P
S
M
L
S
C
D
D
V
N
M
R
I
Frog
Xenopus laevis
NP_001090241
434
47858
S262
P
Q
L
S
G
I
L
S
S
E
S
V
S
L
R
Zebra Danio
Brachydanio rerio
NP_001003621
435
48000
E264
P
R
L
H
A
C
L
E
S
S
E
V
N
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392883
437
48738
N259
N
S
Y
M
P
S
L
N
R
L
R
E
L
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.1
49.8
91.8
N.A.
50.3
50.1
N.A.
61.8
50
57.6
57
N.A.
N.A.
39.1
N.A.
N.A.
Protein Similarity:
100
72.1
67.8
94.5
N.A.
67.2
67.2
N.A.
74.7
67.6
75.7
71.7
N.A.
N.A.
57.9
N.A.
N.A.
P-Site Identity:
100
13.3
53.3
100
N.A.
53.3
53.3
N.A.
60
6.6
66.6
53.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
13.3
73.3
100
N.A.
73.3
73.3
N.A.
93.3
13.3
86.6
53.3
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
10
28
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
46
28
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
10
28
10
10
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
28
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
19
% I
% Lys:
10
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
19
73
0
10
73
82
0
0
10
0
0
19
46
0
% L
% Met:
0
0
0
10
10
0
0
0
0
0
0
0
10
28
0
% M
% Asn:
10
0
0
0
0
0
0
10
0
0
10
19
55
0
0
% N
% Pro:
37
0
19
55
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
19
0
10
19
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
28
0
0
10
0
0
0
10
0
10
0
0
19
73
% R
% Ser:
0
10
0
19
28
10
19
73
46
19
28
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
19
73
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _