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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IFRD2 All Species: 10.3
Human Site: T53 Identified Species: 22.67
UniProt: Q12894 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12894 NP_006755.4 442 48048 T53 E C P S L L S T T A E D S L G
Chimpanzee Pan troglodytes XP_001167735 607 65633 T219 E C P S L L S T T A E D S L G
Rhesus Macaque Macaca mulatta XP_001099740 451 50204 H53 A S I E T M S H C S G Y S D P
Dog Lupus familis XP_541877 441 47736 T53 E C P S L L S T T A E D S L G
Cat Felis silvestris
Mouse Mus musculus P19182 449 49925 S53 I E T M S H C S G Y S D P S S
Rat Rattus norvegicus P20695 449 49764 S53 I E T M S H C S G Y S D P S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508967 464 50902 V80 S T S E V A S V T E E S S G N
Chicken Gallus gallus NP_001001468 434 48793 E53 S F T E D G P E V D E E A T Q
Frog Xenopus laevis NP_001090241 434 47858 V52 S A S E T V S V A E E A A G N
Zebra Danio Brachydanio rerio NP_001003621 435 48000 E52 E S A S V I E E G A G E V V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392883 437 48738 E52 L D D V N D N E V D E F A Q Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.1 49.8 91.8 N.A. 50.3 50.1 N.A. 61.8 50 57.6 57 N.A. N.A. 39.1 N.A. N.A.
Protein Similarity: 100 72.1 67.8 94.5 N.A. 67.2 67.2 N.A. 74.7 67.6 75.7 71.7 N.A. N.A. 57.9 N.A. N.A.
P-Site Identity: 100 100 13.3 100 N.A. 6.6 6.6 N.A. 26.6 6.6 13.3 20 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 13.3 13.3 N.A. 33.3 20 26.6 46.6 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 0 10 0 0 10 37 0 10 28 0 0 % A
% Cys: 0 28 0 0 0 0 19 0 10 0 0 0 0 0 0 % C
% Asp: 0 10 10 0 10 10 0 0 0 19 0 46 0 10 10 % D
% Glu: 37 19 0 37 0 0 10 28 0 19 64 19 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 28 0 19 0 0 19 28 % G
% His: 0 0 0 0 0 19 0 10 0 0 0 0 0 0 0 % H
% Ile: 19 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 28 28 0 0 0 0 0 0 0 28 0 % L
% Met: 0 0 0 19 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 19 % N
% Pro: 0 0 28 0 0 0 10 0 0 0 0 0 19 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 19 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 28 19 19 37 19 0 55 19 0 10 19 10 46 19 19 % S
% Thr: 0 10 28 0 19 0 0 28 37 0 0 0 0 10 0 % T
% Val: 0 0 0 10 19 10 0 19 19 0 0 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 19 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _