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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LMAN2 All Species: 25.15
Human Site: S59 Identified Species: 55.33
UniProt: Q12907 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12907 NP_006807.1 356 40229 S59 E H L K R E H S L I K P Y Q G
Chimpanzee Pan troglodytes XP_001141238 356 40157 S59 E H L K R E H S L I K P Y Q G
Rhesus Macaque Macaca mulatta XP_001094715 279 31618 W13 L V G L A A C W K A P G S S E
Dog Lupus familis XP_863934 348 39900 S56 E Y L K R E H S L S K P Y Q G
Cat Felis silvestris
Mouse Mus musculus Q9DBH5 358 40397 S61 E H L K R E H S L I K P Y Q G
Rat Rattus norvegicus Q62902 517 57939 S59 R R F E Y K Y S F K G P H L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508603 343 38614 P51 G E R V V G D P C S I S P V G
Chicken Gallus gallus
Frog Xenopus laevis NP_001089589 342 39207 S51 E Y L K R E H S L S K P Y Q G
Zebra Danio Brachydanio rerio NP_001075216 354 40230 S56 E H L K R E H S L I K P Y Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625194 324 37133 G39 S L I R P Y Q G S G M S I P Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783719 331 37818 T42 H S L M R P Y T G A G A S L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 75.5 55.3 N.A. 94.1 23 N.A. 51.4 N.A. 54.7 71.3 N.A. N.A. 48.5 N.A. 48.8
Protein Similarity: 100 99.7 76.9 71.3 N.A. 96 37.9 N.A. 66 N.A. 70.7 83.1 N.A. N.A. 64.8 N.A. 65.7
P-Site Identity: 100 100 0 86.6 N.A. 100 13.3 N.A. 6.6 N.A. 86.6 100 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 0 93.3 N.A. 100 40 N.A. 6.6 N.A. 93.3 100 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 10 0 0 0 19 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 55 10 0 10 0 55 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 10 0 10 0 0 10 0 10 10 10 19 10 0 0 64 % G
% His: 10 37 0 0 0 0 55 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 37 10 0 10 0 0 % I
% Lys: 0 0 0 55 0 10 0 0 10 10 55 0 0 0 0 % K
% Leu: 10 10 64 10 0 0 0 0 55 0 0 0 0 19 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 10 0 10 0 0 10 64 10 10 10 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 55 0 % Q
% Arg: 10 10 10 10 64 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 10 0 0 0 0 0 64 10 28 0 19 19 10 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 10 0 10 10 0 0 0 0 0 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 19 0 0 10 10 19 0 0 0 0 0 55 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _