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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LMAN2 All Species: 22.42
Human Site: S69 Identified Species: 49.33
UniProt: Q12907 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12907 NP_006807.1 356 40229 S69 K P Y Q G V G S S S M P L W D
Chimpanzee Pan troglodytes XP_001141238 356 40157 S69 K P Y Q G V G S S S M P L W D
Rhesus Macaque Macaca mulatta XP_001094715 279 31618 V23 P G S S E Q P V L L S L Q P C
Dog Lupus familis XP_863934 348 39900 T66 K P Y Q G V G T G S S S L W N
Cat Felis silvestris
Mouse Mus musculus Q9DBH5 358 40397 S71 K P Y Q G V G S S S M P L W D
Rat Rattus norvegicus Q62902 517 57939 D69 G P H L V Q S D G T V P F W A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508603 343 38614 T61 I S P V G V G T G S S S L W D
Chicken Gallus gallus
Frog Xenopus laevis NP_001089589 342 39207 S61 K P Y Q G V G S S T S S L W D
Zebra Danio Brachydanio rerio NP_001075216 354 40230 S66 K P Y Q G V G S S P S S Q W D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625194 324 37133 F49 M S I P Y W D F T G S T I V T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783719 331 37818 D52 G A S L P M W D I T G N T M V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 75.5 55.3 N.A. 94.1 23 N.A. 51.4 N.A. 54.7 71.3 N.A. N.A. 48.5 N.A. 48.8
Protein Similarity: 100 99.7 76.9 71.3 N.A. 96 37.9 N.A. 66 N.A. 70.7 83.1 N.A. N.A. 64.8 N.A. 65.7
P-Site Identity: 100 100 0 66.6 N.A. 100 20 N.A. 46.6 N.A. 80 73.3 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 0 80 N.A. 100 40 N.A. 53.3 N.A. 86.6 73.3 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 0 10 19 0 0 0 0 0 0 55 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % F
% Gly: 19 10 0 0 64 0 64 0 28 10 10 0 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 10 0 0 0 0 0 10 0 0 0 10 0 0 % I
% Lys: 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 19 0 0 0 0 10 10 0 10 55 0 0 % L
% Met: 10 0 0 0 0 10 0 0 0 0 28 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % N
% Pro: 10 64 10 10 10 0 10 0 0 10 0 37 0 10 0 % P
% Gln: 0 0 0 55 0 19 0 0 0 0 0 0 19 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 19 19 10 0 0 10 46 46 46 55 37 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 19 10 28 0 10 10 0 10 % T
% Val: 0 0 0 10 10 64 0 10 0 0 10 0 0 10 10 % V
% Trp: 0 0 0 0 0 10 10 0 0 0 0 0 0 73 0 % W
% Tyr: 0 0 55 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _