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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LMAN2 All Species: 29.39
Human Site: S96 Identified Species: 64.67
UniProt: Q12907 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12907 NP_006807.1 356 40229 S96 R L T P D E R S K E G S I W N
Chimpanzee Pan troglodytes XP_001141238 356 40157 S96 R L T P D E R S K E G S I W N
Rhesus Macaque Macaca mulatta XP_001094715 279 31618 N50 V H G T G K K N L H G D G I A
Dog Lupus familis XP_863934 348 39900 S93 R L T P D M Q S K Q G A L W N
Cat Felis silvestris
Mouse Mus musculus Q9DBH5 358 40397 S98 R L T P D E R S K E G S I W N
Rat Rattus norvegicus Q62902 517 57939 S96 R I A P S L K S Q R G S V W T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508603 343 38614 S88 R L T P D M Q S K Q G A L W N
Chicken Gallus gallus
Frog Xenopus laevis NP_001089589 342 39207 S88 R L T P D L Q S K Q G A V W N
Zebra Danio Brachydanio rerio NP_001075216 354 40230 S93 R L T P D E R S K Q G S I W N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625194 324 37133 A76 K Q G A I W N A V P C H A R N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783719 331 37818 N79 S M R G A V W N Q V S N K S P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 75.5 55.3 N.A. 94.1 23 N.A. 51.4 N.A. 54.7 71.3 N.A. N.A. 48.5 N.A. 48.8
Protein Similarity: 100 99.7 76.9 71.3 N.A. 96 37.9 N.A. 66 N.A. 70.7 83.1 N.A. N.A. 64.8 N.A. 65.7
P-Site Identity: 100 100 6.6 66.6 N.A. 100 40 N.A. 66.6 N.A. 66.6 93.3 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 100 26.6 93.3 N.A. 100 66.6 N.A. 93.3 N.A. 93.3 100 N.A. N.A. 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 10 0 0 10 0 0 0 28 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 64 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 37 0 0 0 28 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 19 10 10 0 0 0 0 0 82 0 10 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 10 0 10 0 0 0 % H
% Ile: 0 10 0 0 10 0 0 0 0 0 0 0 37 10 0 % I
% Lys: 10 0 0 0 0 10 19 0 64 0 0 0 10 0 0 % K
% Leu: 0 64 0 0 0 19 0 0 10 0 0 0 19 0 0 % L
% Met: 0 10 0 0 0 19 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 19 0 0 0 10 0 0 73 % N
% Pro: 0 0 0 73 0 0 0 0 0 10 0 0 0 0 10 % P
% Gln: 0 10 0 0 0 0 28 0 19 37 0 0 0 0 0 % Q
% Arg: 73 0 10 0 0 0 37 0 0 10 0 0 0 10 0 % R
% Ser: 10 0 0 0 10 0 0 73 0 0 10 46 0 10 0 % S
% Thr: 0 0 64 10 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 10 0 0 0 0 10 0 0 10 10 0 0 19 0 0 % V
% Trp: 0 0 0 0 0 10 10 0 0 0 0 0 0 73 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _