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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS8
All Species:
12.42
Human Site:
S203
Identified Species:
34.17
UniProt:
Q12929
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12929
NP_004438.3
822
91882
S203
P
D
A
L
R
M
I
S
N
A
D
P
S
I
P
Chimpanzee
Pan troglodytes
XP_528750
1001
111581
S406
P
D
A
L
R
M
I
S
N
A
D
P
S
I
P
Rhesus Macaque
Macaca mulatta
XP_001091077
1055
116825
S428
P
D
A
L
R
M
I
S
N
A
D
P
G
I
P
Dog
Lupus familis
XP_534881
791
88639
R202
T
Q
V
D
V
R
S
R
V
A
A
W
S
A
W
Cat
Felis silvestris
Mouse
Mus musculus
Q08509
821
91720
A203
P
E
A
L
R
M
I
A
K
A
D
P
G
I
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416405
831
92642
S206
L
E
T
L
R
M
I
S
S
A
D
G
A
I
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956536
804
88650
D193
L
K
M
I
L
K
S
D
G
S
I
P
P
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392229
880
100126
Q199
N
G
V
N
V
R
E
Q
V
S
A
F
N
A
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785396
970
107261
D333
D
D
R
R
M
R
Y
D
G
D
T
M
Y
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.7
76.1
91.1
N.A.
88.9
N.A.
N.A.
N.A.
79.7
N.A.
51.8
N.A.
N.A.
28.8
N.A.
25.5
Protein Similarity:
100
79
77.1
93.4
N.A.
94.8
N.A.
N.A.
N.A.
88.5
N.A.
66.9
N.A.
N.A.
47.2
N.A.
42.3
P-Site Identity:
100
100
93.3
13.3
N.A.
73.3
N.A.
N.A.
N.A.
60
N.A.
13.3
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
100
100
93.3
13.3
N.A.
86.6
N.A.
N.A.
N.A.
80
N.A.
26.6
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
45
0
0
0
0
12
0
67
23
0
12
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
45
0
12
0
0
0
23
0
12
56
0
0
0
0
% D
% Glu:
0
23
0
0
0
0
12
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
0
12
0
0
0
0
0
0
23
0
0
12
23
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
56
0
0
0
12
0
0
67
0
% I
% Lys:
0
12
0
0
0
12
0
0
12
0
0
0
0
0
0
% K
% Leu:
23
0
0
56
12
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
12
0
12
56
0
0
0
0
0
12
0
0
0
% M
% Asn:
12
0
0
12
0
0
0
0
34
0
0
0
12
0
12
% N
% Pro:
45
0
0
0
0
0
0
0
0
0
0
56
12
12
78
% P
% Gln:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
0
12
12
56
34
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
23
45
12
23
0
0
34
0
0
% S
% Thr:
12
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% T
% Val:
0
0
23
0
23
0
0
0
23
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _