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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRAF2
All Species:
13.64
Human Site:
S453
Identified Species:
42.86
UniProt:
Q12933
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12933
NP_066961.2
501
55859
S453
A
F
R
P
D
V
T
S
S
S
F
Q
R
P
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
B6CJY5
522
59446
L456
I
M
D
A
K
P
D
L
L
A
F
Q
R
P
T
Dog
Lupus familis
XP_857289
501
56059
S453
A
F
R
P
D
V
T
S
S
S
F
Q
R
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P39429
501
56008
S453
A
F
R
P
D
V
T
S
S
S
F
Q
R
P
V
Rat
Rattus norvegicus
B5DF45
530
60235
L464
V
M
D
A
K
P
E
L
L
A
F
Q
R
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415560
507
57256
S459
A
F
R
P
D
V
T
S
S
S
F
Q
R
P
V
Frog
Xenopus laevis
Q6DJN2
556
63191
L490
V
M
D
T
K
P
D
L
L
A
F
Q
R
P
T
Zebra Danio
Brachydanio rerio
Q6IWL4
542
61788
L477
V
M
E
T
K
P
D
L
Q
A
F
Q
R
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
27.5
90.4
N.A.
86.8
28.1
N.A.
N.A.
78.5
25.5
25.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
45.7
94.6
N.A.
92.2
44.1
N.A.
N.A.
87.7
43.7
42
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
26.6
100
N.A.
100
26.6
N.A.
N.A.
100
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
33.3
100
N.A.
100
33.3
N.A.
N.A.
100
33.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
25
0
0
0
0
0
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
38
0
50
0
38
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
13
0
0
0
13
0
0
0
0
0
0
0
0
% E
% Phe:
0
50
0
0
0
0
0
0
0
0
100
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
50
38
0
0
0
0
0
0
% L
% Met:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
50
0
50
0
0
0
0
0
0
0
100
0
% P
% Gln:
0
0
0
0
0
0
0
0
13
0
0
100
0
0
0
% Q
% Arg:
0
0
50
0
0
0
0
0
0
0
0
0
100
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
50
50
0
0
0
0
0
% S
% Thr:
0
0
0
25
0
0
50
0
0
0
0
0
0
0
50
% T
% Val:
38
0
0
0
0
50
0
0
0
0
0
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _