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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXC1
All Species:
3.33
Human Site:
S422
Identified Species:
8.15
UniProt:
Q12948
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12948
NP_001444.2
553
56789
S422
A
P
G
G
A
G
G
S
A
V
D
D
P
L
P
Chimpanzee
Pan troglodytes
XP_001174718
240
23092
P121
P
L
P
D
Y
S
L
P
P
V
T
S
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001119000
442
46184
Q323
T
S
L
R
G
S
P
Q
S
A
A
A
E
L
G
Dog
Lupus familis
XP_546791
479
51548
S359
P
A
L
D
E
A
L
S
D
H
P
S
G
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61572
553
56935
A428
P
A
G
G
A
G
S
A
A
V
D
D
P
L
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990337
528
54812
Y379
A
E
D
P
L
P
D
Y
A
M
P
G
G
G
G
Frog
Xenopus laevis
Q9PVZ3
492
53656
S371
M
Q
A
M
S
L
Y
S
G
D
R
S
G
H
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32027
508
54498
T370
P
H
N
G
Q
Q
G
T
P
T
H
P
G
H
N
Honey Bee
Apis mellifera
XP_001121752
495
55049
T370
S
V
C
T
T
T
T
T
T
T
A
A
V
A
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780709
519
57235
A385
S
Y
D
P
E
S
M
A
M
G
K
H
M
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
79.1
50.2
N.A.
93.4
N.A.
N.A.
N.A.
57.3
69.9
N.A.
N.A.
32.3
31.1
N.A.
35
Protein Similarity:
100
43.2
79.3
60.7
N.A.
95.1
N.A.
N.A.
N.A.
62.5
75.5
N.A.
N.A.
43.2
42.5
N.A.
48.6
P-Site Identity:
100
6.6
6.6
6.6
N.A.
73.3
N.A.
N.A.
N.A.
13.3
6.6
N.A.
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
6.6
13.3
6.6
N.A.
80
N.A.
N.A.
N.A.
20
13.3
N.A.
N.A.
20
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
10
0
20
10
0
20
30
10
20
20
0
20
20
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
20
0
0
10
0
10
10
20
20
0
0
0
% D
% Glu:
0
10
0
0
20
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
20
30
10
20
20
0
10
10
0
10
40
10
20
% G
% His:
0
10
0
0
0
0
0
0
0
10
10
10
0
20
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
10
20
0
10
10
20
0
0
0
0
0
0
30
10
% L
% Met:
10
0
0
10
0
0
10
0
10
10
0
0
10
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
40
10
10
20
0
10
10
10
20
0
20
10
20
10
20
% P
% Gln:
0
10
0
0
10
10
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
20
10
0
0
10
30
10
30
10
0
0
30
10
10
10
% S
% Thr:
10
0
0
10
10
10
10
20
10
20
10
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
30
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
0
10
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _