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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXC1 All Species: 7.27
Human Site: T368 Identified Species: 17.78
UniProt: Q12948 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12948 NP_001444.2 553 56789 T368 Y S S P C S Q T S S A G S S G
Chimpanzee Pan troglodytes XP_001174718 240 23092 A74 G A G G A G G A G G A G T Y H
Rhesus Macaque Macaca mulatta XP_001119000 442 46184 S276 S G S S P P G S L P S A R P L
Dog Lupus familis XP_546791 479 51548 A312 Y A A A P P A A Y G Q P C A Q
Cat Felis silvestris
Mouse Mus musculus Q61572 553 56935 S368 Y S S P C S Q S S S A G S S G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_990337 528 54812 C331 S A V Y G S P C G Q P A A A A
Frog Xenopus laevis Q9PVZ3 492 53656 S322 L P S P L I S S S R T G I A P
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P32027 508 54498 P320 H V A H V A H P L T P G G Q G
Honey Bee Apis mellifera XP_001121752 495 55049 L319 T R E N S A A L M T R E N Q H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780709 519 57235 G337 Q A L P P R T G Q L L S P Q P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.2 79.1 50.2 N.A. 93.4 N.A. N.A. N.A. 57.3 69.9 N.A. N.A. 32.3 31.1 N.A. 35
Protein Similarity: 100 43.2 79.3 60.7 N.A. 95.1 N.A. N.A. N.A. 62.5 75.5 N.A. N.A. 43.2 42.5 N.A. 48.6
P-Site Identity: 100 13.3 6.6 6.6 N.A. 93.3 N.A. N.A. N.A. 6.6 26.6 N.A. N.A. 13.3 0 N.A. 6.6
P-Site Similarity: 100 26.6 20 26.6 N.A. 100 N.A. N.A. N.A. 26.6 40 N.A. N.A. 40 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 40 20 10 10 20 20 20 0 0 30 20 10 30 10 % A
% Cys: 0 0 0 0 20 0 0 10 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 10 10 10 10 20 10 20 20 0 50 10 0 30 % G
% His: 10 0 0 10 0 0 10 0 0 0 0 0 0 0 20 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 0 10 0 0 10 20 10 10 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 10 0 40 30 20 10 10 0 10 20 10 10 10 20 % P
% Gln: 10 0 0 0 0 0 20 0 10 10 10 0 0 30 10 % Q
% Arg: 0 10 0 0 0 10 0 0 0 10 10 0 10 0 0 % R
% Ser: 20 20 40 10 10 30 10 30 30 20 10 10 20 20 0 % S
% Thr: 10 0 0 0 0 0 10 10 0 20 10 0 10 0 0 % T
% Val: 0 10 10 0 10 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 30 0 0 10 0 0 0 0 10 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _