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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXD4 All Species: 18.48
Human Site: S128 Identified Species: 40.67
UniProt: Q12950 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12950 NP_997188.2 439 47251 S128 P H K R L T L S G I C A F I S
Chimpanzee Pan troglodytes NP_001009014 413 45421 S128 P H K R L T L S G I C A F I S
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q60688 444 48029 S127 P H K R L T L S G I C A F I S
Rat Rattus norvegicus Q63245 101 11924
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516678 728 77542 S250 P H K R L T L S G I C A F I S
Chicken Gallus gallus P79772 394 40977 K110 A A A A G Q S K P K S S L V K
Frog Xenopus laevis Q9DEN4 371 40000 A101 K P P Y S Y I A L I T M S I L
Zebra Danio Brachydanio rerio NP_571365 371 40457 Y101 L V K P P Y S Y I A L I T M A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02361 456 49036 S109 P H K K L T L S G I C D F I M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496411 333 37274 R62 D L K F G E S R K R S R S L G
Sea Urchin Strong. purpuratus XP_001188749 401 43606 K111 K S E T A D D K K K A I S V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.6 N.A. N.A. N.A. 48.6 20.5 N.A. 33 38.2 34.8 32.7 N.A. 30.9 N.A. 31.2 34.8
Protein Similarity: 100 83.1 N.A. N.A. N.A. 55.6 21.6 N.A. 41.4 46.7 46.4 45.3 N.A. 44 N.A. 43.2 44.8
P-Site Identity: 100 100 N.A. N.A. N.A. 100 0 N.A. 100 0 13.3 6.6 N.A. 80 N.A. 6.6 0
P-Site Similarity: 100 100 N.A. N.A. N.A. 100 0 N.A. 100 13.3 26.6 20 N.A. 86.6 N.A. 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 10 10 0 0 10 0 10 10 37 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 46 0 0 0 0 % C
% Asp: 10 0 0 0 0 10 10 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 46 0 0 % F
% Gly: 0 0 0 0 19 0 0 0 46 0 0 0 0 0 10 % G
% His: 0 46 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 10 55 0 19 0 55 0 % I
% Lys: 19 0 64 10 0 0 0 19 19 19 0 0 0 0 19 % K
% Leu: 10 10 0 0 46 0 46 0 10 0 10 0 10 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 46 10 10 10 10 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 37 0 0 0 10 0 10 0 10 0 0 0 % R
% Ser: 0 10 0 0 10 0 28 46 0 0 19 10 28 0 37 % S
% Thr: 0 0 0 10 0 46 0 0 0 0 10 0 10 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 0 0 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 19 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _