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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXD4
All Species:
2.21
Human Site:
S435
Identified Species:
4.86
UniProt:
Q12950
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12950
NP_997188.2
439
47251
S435
T
P
S
S
L
A
E
S
A
G
P
S
_
_
_
Chimpanzee
Pan troglodytes
NP_001009014
413
45421
T406
R
A
R
C
W
A
G
T
C
R
P
R
R
R
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q60688
444
48029
E438
L
A
A
L
S
G
R
E
G
T
L
P
E
F
_
Rat
Rattus norvegicus
Q63245
101
11924
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516678
728
77542
L579
P
R
E
D
C
L
P
L
R
R
K
D
L
V
L
Chicken
Gallus gallus
P79772
394
40977
K390
P
P
A
A
V
Q
A
K
W
P
A
Q
_
_
_
Frog
Xenopus laevis
Q9DEN4
371
40000
Zebra Danio
Brachydanio rerio
NP_571365
371
40457
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02361
456
49036
E452
L
H
R
G
G
S
Q
E
E
T
S
D
_
_
_
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496411
333
37274
Sea Urchin
Strong. purpuratus
XP_001188749
401
43606
T395
F
Q
C
T
R
Q
P
T
S
T
C
N
W
R
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.6
N.A.
N.A.
N.A.
48.6
20.5
N.A.
33
38.2
34.8
32.7
N.A.
30.9
N.A.
31.2
34.8
Protein Similarity:
100
83.1
N.A.
N.A.
N.A.
55.6
21.6
N.A.
41.4
46.7
46.4
45.3
N.A.
44
N.A.
43.2
44.8
P-Site Identity:
100
13.3
N.A.
N.A.
N.A.
0
0
N.A.
0
8.3
0
0
N.A.
0
N.A.
0
0
P-Site Similarity:
100
20
N.A.
N.A.
N.A.
7.1
0
N.A.
0
33.3
0
0
N.A.
16.6
N.A.
0
28.5
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
19
10
0
19
10
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
10
10
10
0
0
0
10
0
10
0
0
0
10
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
19
0
0
0
% D
% Glu:
0
0
10
0
0
0
10
19
10
0
0
0
10
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
10
10
10
10
0
10
10
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% K
% Leu:
19
0
0
10
10
10
0
10
0
0
10
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
19
19
0
0
0
0
19
0
0
10
19
10
0
0
0
% P
% Gln:
0
10
0
0
0
19
10
0
0
0
0
10
0
0
0
% Q
% Arg:
10
10
19
0
10
0
10
0
10
19
0
10
10
19
0
% R
% Ser:
0
0
10
10
10
10
0
10
10
0
10
10
0
0
0
% S
% Thr:
10
0
0
10
0
0
0
19
0
28
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
10
0
0
0
10
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
28
28
46
% _