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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXL1 All Species: 9.09
Human Site: S258 Identified Species: 20
UniProt: Q12952 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12952 NP_005241.1 345 36490 S258 S P K S S D K S K S F S I D S
Chimpanzee Pan troglodytes XP_511154 345 36647 S258 S P K S S D K S K S F S I D S
Rhesus Macaque Macaca mulatta XP_001087392 230 25701 G148 R K R K P K P G P G A P E A K
Dog Lupus familis XP_851625 356 37589 S269 S P K S S D K S K S F S I D S
Cat Felis silvestris
Mouse Mus musculus Q64731 337 36523 K253 L P K R F Q V K E F Q H R Q H
Rat Rattus norvegicus Q63246 101 12079 A19 S T M A I Q N A P E K K I T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001231599 358 38914 A248 S P G A V P K A R E S P V G S
Frog Xenopus laevis Q9PVY8 461 51127 N351 E A T S E H H N G T S S P L N
Zebra Danio Brachydanio rerio NP_957278 363 39971 A265 V K S D T G R A Q S G D A K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P32027 508 54498 G349 T P H G P A H G G W Y T P E T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784909 521 58470 K296 Y S R P E V R K P V F S I D N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 52.7 85.1 N.A. 67.2 22 N.A. N.A. 43.5 31.2 38.8 N.A. 30.1 N.A. N.A. 28.9
Protein Similarity: 100 98.5 57.9 87 N.A. 72.4 27.5 N.A. N.A. 54.1 44.6 48.7 N.A. 40.9 N.A. N.A. 40.8
P-Site Identity: 100 100 0 100 N.A. 13.3 13.3 N.A. N.A. 26.6 13.3 13.3 N.A. 6.6 N.A. N.A. 26.6
P-Site Similarity: 100 100 6.6 100 N.A. 20 26.6 N.A. N.A. 53.3 33.3 40 N.A. 40 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 19 0 10 0 28 0 0 10 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 28 0 0 0 0 0 10 0 37 0 % D
% Glu: 10 0 0 0 19 0 0 0 10 19 0 0 10 10 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 10 37 0 0 0 0 % F
% Gly: 0 0 10 10 0 10 0 19 19 10 10 0 0 10 0 % G
% His: 0 0 10 0 0 10 19 0 0 0 0 10 0 0 10 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 46 0 0 % I
% Lys: 0 19 37 10 0 10 37 19 28 0 10 10 0 10 10 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 19 % N
% Pro: 0 55 0 10 19 10 10 0 28 0 0 19 19 0 0 % P
% Gln: 0 0 0 0 0 19 0 0 10 0 10 0 0 10 0 % Q
% Arg: 10 0 19 10 0 0 19 0 10 0 0 0 10 0 0 % R
% Ser: 46 10 10 37 28 0 0 28 0 37 19 46 0 0 46 % S
% Thr: 10 10 10 0 10 0 0 0 0 10 0 10 0 10 10 % T
% Val: 10 0 0 0 10 10 10 0 0 10 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _