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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1E
All Species:
31.52
Human Site:
S843
Identified Species:
57.78
UniProt:
Q12965
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12965
NP_004989.2
1108
127062
S843
L
H
E
Q
E
Y
D
S
L
L
E
S
V
F
K
Chimpanzee
Pan troglodytes
XP_510448
1108
126943
S843
L
H
E
Q
E
Y
D
S
L
L
E
S
V
F
K
Rhesus Macaque
Macaca mulatta
XP_001100995
715
80188
M468
L
D
D
V
C
A
T
M
H
A
T
G
G
G
A
Dog
Lupus familis
XP_535500
1130
129758
S865
L
H
E
Q
E
Y
D
S
L
L
E
S
V
F
K
Cat
Felis silvestris
Mouse
Mus musculus
P70248
1099
125929
T841
L
Q
E
E
A
A
D
T
F
L
E
S
I
F
K
Rat
Rattus norvegicus
Q63356
1107
126808
S843
L
H
E
Q
E
Y
D
S
L
L
E
S
V
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLA6
1028
118889
F781
L
D
Y
I
R
F
S
F
L
M
N
L
K
R
N
Frog
Xenopus laevis
NP_001080439
1094
125660
S841
L
H
E
A
Q
Y
D
S
V
L
E
T
M
F
K
Zebra Danio
Brachydanio rerio
XP_682849
1163
133360
S900
L
H
E
D
E
Y
D
S
L
L
E
C
V
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492393
1100
124867
S843
L
G
N
D
D
Y
S
S
L
L
E
T
P
F
K
Sea Urchin
Strong. purpuratus
NP_001118234
1118
127023
S837
H
V
S
E
E
Y
D
S
I
L
E
S
T
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04439
1219
136881
A881
N
L
Q
D
D
W
V
A
I
K
L
A
S
S
G
Red Bread Mold
Neurospora crassa
Q7SDM3
1235
136290
G873
L
A
S
I
K
F
I
G
A
S
T
A
R
D
D
Conservation
Percent
Protein Identity:
100
99.6
49.9
96.2
N.A.
70.4
95.6
N.A.
N.A.
35.8
75.5
77.7
N.A.
N.A.
N.A.
56.9
63.4
Protein Similarity:
100
99.8
56.5
97.4
N.A.
82
98
N.A.
N.A.
54.2
86.6
86.6
N.A.
N.A.
N.A.
71.7
78.7
P-Site Identity:
100
100
6.6
100
N.A.
53.3
100
N.A.
N.A.
13.3
66.6
86.6
N.A.
N.A.
N.A.
53.3
60
P-Site Similarity:
100
100
13.3
100
N.A.
73.3
100
N.A.
N.A.
26.6
93.3
86.6
N.A.
N.A.
N.A.
66.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.7
38
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.5
54.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
16
0
8
8
8
0
16
0
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
16
8
24
16
0
62
0
0
0
0
0
0
8
8
% D
% Glu:
0
0
54
16
47
0
0
0
0
0
70
0
0
0
0
% E
% Phe:
0
0
0
0
0
16
0
8
8
0
0
0
0
70
0
% F
% Gly:
0
8
0
0
0
0
0
8
0
0
0
8
8
8
8
% G
% His:
8
47
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
0
0
8
0
16
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
8
0
0
8
0
70
% K
% Leu:
85
8
0
0
0
0
0
0
54
70
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
0
8
0
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
0
8
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
8
8
31
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
8
8
0
% R
% Ser:
0
0
16
0
0
0
16
62
0
8
0
47
8
8
0
% S
% Thr:
0
0
0
0
0
0
8
8
0
0
16
16
8
0
0
% T
% Val:
0
8
0
8
0
0
8
0
8
0
0
0
39
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
62
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _