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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1E
All Species:
27.27
Human Site:
S919
Identified Species:
50
UniProt:
Q12965
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12965
NP_004989.2
1108
127062
S919
S
N
K
V
L
Q
V
S
I
G
P
G
L
P
K
Chimpanzee
Pan troglodytes
XP_510448
1108
126943
S919
S
N
K
V
L
Q
V
S
I
G
P
G
L
P
K
Rhesus Macaque
Macaca mulatta
XP_001100995
715
80188
R541
T
S
E
Q
A
F
L
R
M
L
F
P
E
K
L
Dog
Lupus familis
XP_535500
1130
129758
S941
S
N
K
V
L
Q
V
S
I
G
P
G
L
P
K
Cat
Felis silvestris
Mouse
Mus musculus
P70248
1099
125929
S914
G
G
K
T
L
T
I
S
L
G
D
G
L
P
K
Rat
Rattus norvegicus
Q63356
1107
126808
V918
P
S
N
K
V
L
Q
V
S
I
G
P
G
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLA6
1028
118889
P854
K
G
K
K
D
N
Y
P
Q
S
V
P
R
L
F
Frog
Xenopus laevis
NP_001080439
1094
125660
S917
N
G
K
V
L
V
I
S
I
G
Q
G
L
P
P
Zebra Danio
Brachydanio rerio
XP_682849
1163
133360
S976
S
N
K
M
L
Q
V
S
I
G
P
G
L
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492393
1100
124867
S919
N
G
K
V
L
N
V
S
I
G
T
G
L
P
N
Sea Urchin
Strong. purpuratus
NP_001118234
1118
127023
S910
S
S
K
I
L
T
V
S
I
G
S
G
L
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04439
1219
136881
G958
S
T
I
S
V
R
R
G
N
P
P
N
S
Q
V
Red Bread Mold
Neurospora crassa
Q7SDM3
1235
136290
H955
F
Y
K
S
S
T
V
H
T
Q
P
G
E
P
P
Conservation
Percent
Protein Identity:
100
99.6
49.9
96.2
N.A.
70.4
95.6
N.A.
N.A.
35.8
75.5
77.7
N.A.
N.A.
N.A.
56.9
63.4
Protein Similarity:
100
99.8
56.5
97.4
N.A.
82
98
N.A.
N.A.
54.2
86.6
86.6
N.A.
N.A.
N.A.
71.7
78.7
P-Site Identity:
100
100
0
100
N.A.
53.3
0
N.A.
N.A.
6.6
60
93.3
N.A.
N.A.
N.A.
66.6
66.6
P-Site Similarity:
100
100
33.3
100
N.A.
66.6
13.3
N.A.
N.A.
6.6
73.3
100
N.A.
N.A.
N.A.
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.7
38
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.5
54.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
16
0
0
% E
% Phe:
8
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% F
% Gly:
8
31
0
0
0
0
0
8
0
62
8
70
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
16
0
54
8
0
0
0
0
0
% I
% Lys:
8
0
77
16
0
0
0
0
0
0
0
0
0
8
39
% K
% Leu:
0
0
0
0
62
8
8
0
8
8
0
0
62
16
8
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
16
31
8
0
0
16
0
0
8
0
0
8
0
0
8
% N
% Pro:
8
0
0
0
0
0
0
8
0
8
47
24
0
70
24
% P
% Gln:
0
0
0
8
0
31
8
0
8
8
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
8
8
0
0
0
0
8
0
8
% R
% Ser:
47
24
0
16
8
0
0
62
8
8
8
0
8
0
0
% S
% Thr:
8
8
0
8
0
24
0
0
8
0
8
0
0
0
0
% T
% Val:
0
0
0
39
16
8
54
8
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _