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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1E
All Species:
17.27
Human Site:
S991
Identified Species:
31.67
UniProt:
Q12965
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12965
NP_004989.2
1108
127062
S991
N
Q
K
S
L
Y
T
S
M
A
R
P
P
L
P
Chimpanzee
Pan troglodytes
XP_510448
1108
126943
S991
N
Q
K
S
L
Y
T
S
M
A
R
P
P
L
P
Rhesus Macaque
Macaca mulatta
XP_001100995
715
80188
R613
L
G
A
S
R
R
P
R
A
Q
L
P
S
E
H
Dog
Lupus familis
XP_535500
1130
129758
S1013
N
Q
K
S
L
Y
T
S
M
A
R
P
P
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P70248
1099
125929
I986
F
P
E
A
S
T
A
I
H
L
Q
P
Q
D
A
Rat
Rattus norvegicus
Q63356
1107
126808
S990
N
Q
K
S
L
Y
T
S
M
A
R
P
P
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLA6
1028
118889
Y926
K
I
K
Q
R
I
D
Y
A
N
L
T
G
I
S
Frog
Xenopus laevis
NP_001080439
1094
125660
K989
Q
G
A
S
P
R
A
K
A
P
P
T
P
V
N
Zebra Danio
Brachydanio rerio
XP_682849
1163
133360
F1048
S
E
N
T
A
R
P
F
L
P
T
N
V
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492393
1100
124867
T991
Q
T
P
A
P
V
S
T
N
H
Q
Y
S
Q
E
Sea Urchin
Strong. purpuratus
NP_001118234
1118
127023
S982
Q
K
R
G
G
P
T
S
P
T
K
G
G
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04439
1219
136881
N1030
A
T
R
R
S
V
P
N
P
A
S
T
L
T
A
Red Bread Mold
Neurospora crassa
Q7SDM3
1235
136290
A1027
P
L
A
S
S
A
A
A
A
S
S
R
P
V
P
Conservation
Percent
Protein Identity:
100
99.6
49.9
96.2
N.A.
70.4
95.6
N.A.
N.A.
35.8
75.5
77.7
N.A.
N.A.
N.A.
56.9
63.4
Protein Similarity:
100
99.8
56.5
97.4
N.A.
82
98
N.A.
N.A.
54.2
86.6
86.6
N.A.
N.A.
N.A.
71.7
78.7
P-Site Identity:
100
100
13.3
100
N.A.
6.6
100
N.A.
N.A.
6.6
13.3
0
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
13.3
100
N.A.
26.6
100
N.A.
N.A.
13.3
20
26.6
N.A.
N.A.
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.7
38
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.5
54.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
24
16
8
8
24
8
31
39
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% D
% Glu:
0
8
8
0
0
0
0
0
0
0
0
0
0
8
8
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
16
0
8
8
0
0
0
0
0
0
8
16
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
8
0
8
0
0
0
0
0
8
0
% I
% Lys:
8
8
39
0
0
0
0
8
0
0
8
0
0
0
8
% K
% Leu:
8
8
0
0
31
0
0
0
8
8
16
0
8
31
0
% L
% Met:
0
0
0
0
0
0
0
0
31
0
0
0
0
8
0
% M
% Asn:
31
0
8
0
0
0
0
8
8
8
0
8
0
0
8
% N
% Pro:
8
8
8
0
16
8
24
0
16
16
8
47
47
0
39
% P
% Gln:
24
31
0
8
0
0
0
0
0
8
16
0
8
8
8
% Q
% Arg:
0
0
16
8
16
24
0
8
0
0
31
8
0
0
0
% R
% Ser:
8
0
0
54
24
0
8
39
0
8
16
0
16
8
8
% S
% Thr:
0
16
0
8
0
8
39
8
0
8
8
24
0
8
0
% T
% Val:
0
0
0
0
0
16
0
0
0
0
0
0
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
31
0
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _