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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1E
All Species:
32.73
Human Site:
T559
Identified Species:
60
UniProt:
Q12965
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12965
NP_004989.2
1108
127062
T559
A
D
K
K
G
R
P
T
T
A
G
S
K
I
K
Chimpanzee
Pan troglodytes
XP_510448
1108
126943
T559
A
D
K
K
G
R
P
T
T
A
G
S
K
I
K
Rhesus Macaque
Macaca mulatta
XP_001100995
715
80188
I209
E
N
E
R
N
F
H
I
Y
Y
Q
L
L
E
G
Dog
Lupus familis
XP_535500
1130
129758
T581
A
D
K
K
G
R
P
T
T
A
G
S
K
I
K
Cat
Felis silvestris
Mouse
Mus musculus
P70248
1099
125929
S557
I
D
K
K
G
R
P
S
T
A
G
S
K
I
K
Rat
Rattus norvegicus
Q63356
1107
126808
T559
A
D
K
K
G
R
P
T
T
A
G
S
K
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLA6
1028
118889
G522
E
V
T
Y
S
V
A
G
F
L
D
K
N
N
D
Frog
Xenopus laevis
NP_001080439
1094
125660
S557
A
E
K
K
G
R
P
S
T
A
G
T
K
I
K
Zebra Danio
Brachydanio rerio
XP_682849
1163
133360
T616
A
E
K
K
G
R
P
T
T
A
G
S
K
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492393
1100
124867
T557
A
S
A
G
K
R
P
T
T
F
S
T
K
I
R
Sea Urchin
Strong. purpuratus
NP_001118234
1118
127023
T552
G
Q
A
K
S
R
P
T
T
A
S
S
K
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04439
1219
136881
P578
R
E
S
K
R
R
P
P
T
A
G
D
K
I
I
Red Bread Mold
Neurospora crassa
Q7SDM3
1235
136290
P578
L
D
N
R
R
Q
P
P
S
A
G
D
R
I
R
Conservation
Percent
Protein Identity:
100
99.6
49.9
96.2
N.A.
70.4
95.6
N.A.
N.A.
35.8
75.5
77.7
N.A.
N.A.
N.A.
56.9
63.4
Protein Similarity:
100
99.8
56.5
97.4
N.A.
82
98
N.A.
N.A.
54.2
86.6
86.6
N.A.
N.A.
N.A.
71.7
78.7
P-Site Identity:
100
100
0
100
N.A.
86.6
100
N.A.
N.A.
0
80
93.3
N.A.
N.A.
N.A.
46.6
66.6
P-Site Similarity:
100
100
20
100
N.A.
93.3
100
N.A.
N.A.
0
100
100
N.A.
N.A.
N.A.
60
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.7
38
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.5
54.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
16
0
0
0
8
0
0
77
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
47
0
0
0
0
0
0
0
0
8
16
0
0
8
% D
% Glu:
16
24
8
0
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
8
8
0
0
0
0
0
% F
% Gly:
8
0
0
8
54
0
0
8
0
0
70
0
0
0
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
8
0
0
0
0
0
85
8
% I
% Lys:
0
0
54
70
8
0
0
0
0
0
0
8
77
0
62
% K
% Leu:
8
0
0
0
0
0
0
0
0
8
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
8
0
0
0
0
0
0
0
8
8
0
% N
% Pro:
0
0
0
0
0
0
85
16
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
0
% Q
% Arg:
8
0
0
16
16
77
0
0
0
0
0
0
8
0
16
% R
% Ser:
0
8
8
0
16
0
0
16
8
0
16
54
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
54
77
0
0
16
0
0
0
% T
% Val:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _