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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1E
All Species:
25.15
Human Site:
T876
Identified Species:
46.11
UniProt:
Q12965
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12965
NP_004989.2
1108
127062
T876
L
P
L
K
F
S
N
T
L
E
L
K
L
K
K
Chimpanzee
Pan troglodytes
XP_510448
1108
126943
T876
L
P
L
K
F
S
N
T
L
E
L
K
L
K
K
Rhesus Macaque
Macaca mulatta
XP_001100995
715
80188
V501
N
S
W
S
A
G
F
V
I
H
H
Y
A
G
K
Dog
Lupus familis
XP_535500
1130
129758
T898
L
P
L
K
F
S
N
T
L
E
L
K
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
P70248
1099
125929
I874
L
P
L
T
F
Q
D
I
L
Q
F
R
V
K
K
Rat
Rattus norvegicus
Q63356
1107
126808
T876
L
P
L
K
F
S
N
T
L
E
L
K
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLA6
1028
118889
Q814
E
A
S
Q
L
L
R
Q
L
C
M
Q
N
M
V
Frog
Xenopus laevis
NP_001080439
1094
125660
Q874
L
P
I
K
F
S
N
Q
L
E
F
K
V
K
K
Zebra Danio
Brachydanio rerio
XP_682849
1163
133360
T933
L
P
L
K
Y
S
N
T
M
E
M
K
L
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492393
1100
124867
S876
L
H
L
D
F
R
S
S
H
V
V
S
Y
K
K
Sea Urchin
Strong. purpuratus
NP_001118234
1118
127023
S870
L
M
V
N
F
N
D
S
I
E
F
S
V
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04439
1219
136881
Q914
K
R
L
N
D
K
I
Q
I
K
I
G
S
A
I
Red Bread Mold
Neurospora crassa
Q7SDM3
1235
136290
T906
V
L
K
T
E
M
F
T
Q
M
K
R
V
M
P
Conservation
Percent
Protein Identity:
100
99.6
49.9
96.2
N.A.
70.4
95.6
N.A.
N.A.
35.8
75.5
77.7
N.A.
N.A.
N.A.
56.9
63.4
Protein Similarity:
100
99.8
56.5
97.4
N.A.
82
98
N.A.
N.A.
54.2
86.6
86.6
N.A.
N.A.
N.A.
71.7
78.7
P-Site Identity:
100
100
6.6
100
N.A.
46.6
100
N.A.
N.A.
6.6
73.3
80
N.A.
N.A.
N.A.
33.3
33.3
P-Site Similarity:
100
100
13.3
100
N.A.
73.3
100
N.A.
N.A.
26.6
86.6
100
N.A.
N.A.
N.A.
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.7
38
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.5
54.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
0
0
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
16
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
8
0
0
0
0
54
0
0
0
0
0
% E
% Phe:
0
0
0
0
62
0
16
0
0
0
24
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
8
0
8
0
% G
% His:
0
8
0
0
0
0
0
0
8
8
8
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
8
24
0
8
0
0
0
8
% I
% Lys:
8
0
8
47
0
8
0
0
0
8
8
47
0
70
77
% K
% Leu:
70
8
62
0
8
8
0
0
54
0
31
0
39
0
0
% L
% Met:
0
8
0
0
0
8
0
0
8
8
16
0
0
16
0
% M
% Asn:
8
0
0
16
0
8
47
0
0
0
0
0
8
0
0
% N
% Pro:
0
54
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
8
0
8
0
24
8
8
0
8
0
0
0
% Q
% Arg:
0
8
0
0
0
8
8
0
0
0
0
16
0
0
0
% R
% Ser:
0
8
8
8
0
47
8
16
0
0
0
16
8
0
0
% S
% Thr:
0
0
0
16
0
0
0
47
0
0
0
0
0
0
0
% T
% Val:
8
0
8
0
0
0
0
8
0
8
8
0
31
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _