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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1E
All Species:
8.79
Human Site:
T939
Identified Species:
16.11
UniProt:
Q12965
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12965
NP_004989.2
1108
127062
T939
R
R
N
T
T
Q
N
T
G
Y
S
S
G
T
Q
Chimpanzee
Pan troglodytes
XP_510448
1108
126943
T939
R
R
N
T
T
Q
N
T
G
Y
S
S
G
T
Q
Rhesus Macaque
Macaca mulatta
XP_001100995
715
80188
S561
G
R
P
S
T
A
G
S
K
I
K
V
G
L
G
Dog
Lupus familis
XP_535500
1130
129758
R961
R
R
N
T
I
Q
N
R
G
Y
P
S
G
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
P70248
1099
125929
K934
R
K
G
L
A
Q
G
K
P
R
R
S
A
Q
A
Rat
Rattus norvegicus
Q63356
1107
126808
S938
T
R
R
N
T
V
S
S
R
G
Y
S
G
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLA6
1028
118889
K874
G
N
E
E
I
N
A
K
V
L
Q
A
L
E
N
Frog
Xenopus laevis
NP_001080439
1094
125660
Q937
R
K
D
N
R
K
S
Q
Y
L
N
S
T
P
A
Zebra Danio
Brachydanio rerio
XP_682849
1163
133360
Q996
K
K
G
I
T
Q
S
Q
P
N
R
S
R
T
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492393
1100
124867
Y939
T
E
R
P
Q
G
G
Y
T
P
R
R
D
Q
L
Sea Urchin
Strong. purpuratus
NP_001118234
1118
127023
S930
L
R
D
V
K
V
T
S
K
D
R
Q
A
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04439
1219
136881
G978
K
K
S
S
I
S
S
G
Y
H
A
S
S
S
Q
Red Bread Mold
Neurospora crassa
Q7SDM3
1235
136290
V975
P
Q
P
K
A
K
P
V
P
P
R
P
I
T
K
Conservation
Percent
Protein Identity:
100
99.6
49.9
96.2
N.A.
70.4
95.6
N.A.
N.A.
35.8
75.5
77.7
N.A.
N.A.
N.A.
56.9
63.4
Protein Similarity:
100
99.8
56.5
97.4
N.A.
82
98
N.A.
N.A.
54.2
86.6
86.6
N.A.
N.A.
N.A.
71.7
78.7
P-Site Identity:
100
100
20
80
N.A.
20
26.6
N.A.
N.A.
0
13.3
26.6
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
33.3
80
N.A.
26.6
40
N.A.
N.A.
6.6
46.6
46.6
N.A.
N.A.
N.A.
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.7
38
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.5
54.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
8
8
0
0
0
8
8
16
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
0
0
0
0
0
8
0
0
8
0
0
% D
% Glu:
0
8
8
8
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
16
0
0
8
24
8
24
8
0
0
39
16
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
0
0
0
8
24
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
16
31
0
8
8
16
0
16
16
0
8
0
0
0
8
% K
% Leu:
8
0
0
8
0
0
0
0
0
16
0
0
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
24
16
0
8
24
0
0
8
8
0
0
0
16
% N
% Pro:
8
0
16
8
0
0
8
0
24
16
8
8
0
8
0
% P
% Gln:
0
8
0
0
8
39
0
16
0
0
8
8
0
16
31
% Q
% Arg:
39
47
16
0
8
0
0
8
8
8
39
8
8
0
0
% R
% Ser:
0
0
8
16
0
8
31
24
0
0
16
62
8
8
0
% S
% Thr:
16
0
0
24
39
0
8
16
8
0
0
0
8
39
8
% T
% Val:
0
0
0
8
0
16
0
8
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
16
24
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _