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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1E
All Species:
18.48
Human Site:
Y236
Identified Species:
33.89
UniProt:
Q12965
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12965
NP_004989.2
1108
127062
Y236
I
T
S
M
D
Y
Y
Y
Y
L
S
L
S
G
S
Chimpanzee
Pan troglodytes
XP_510448
1108
126943
Y236
I
T
S
M
D
Y
Y
Y
Y
L
S
L
S
G
S
Rhesus Macaque
Macaca mulatta
XP_001100995
715
80188
Dog
Lupus familis
XP_535500
1130
129758
Y258
I
T
S
M
D
Y
Y
Y
Y
L
S
L
S
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P70248
1099
125929
L236
S
Q
D
Y
Y
Y
Y
L
N
Q
S
D
T
Y
K
Rat
Rattus norvegicus
Q63356
1107
126808
Y236
I
T
S
M
D
Y
Y
Y
Y
L
S
L
S
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLA6
1028
118889
V233
P
Q
Q
Y
H
Y
L
V
K
G
H
C
A
R
V
Frog
Xenopus laevis
NP_001080439
1094
125660
N237
P
D
Y
Y
F
Y
L
N
Q
S
S
V
Y
H
V
Zebra Danio
Brachydanio rerio
XP_682849
1163
133360
T293
I
T
S
L
D
Y
Y
T
Y
L
N
Q
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492393
1100
124867
K240
L
N
M
S
G
V
F
K
A
D
D
T
D
D
G
Sea Urchin
Strong. purpuratus
NP_001118234
1118
127023
G236
Y
F
Y
L
N
Q
S
G
S
Y
K
V
D
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04439
1219
136881
Y253
G
V
Q
K
P
E
Q
Y
V
Y
T
A
A
A
G
Red Bread Mold
Neurospora crassa
Q7SDM3
1235
136290
L259
I
Q
K
P
E
T
Y
L
Y
T
S
K
A
K
C
Conservation
Percent
Protein Identity:
100
99.6
49.9
96.2
N.A.
70.4
95.6
N.A.
N.A.
35.8
75.5
77.7
N.A.
N.A.
N.A.
56.9
63.4
Protein Similarity:
100
99.8
56.5
97.4
N.A.
82
98
N.A.
N.A.
54.2
86.6
86.6
N.A.
N.A.
N.A.
71.7
78.7
P-Site Identity:
100
100
0
100
N.A.
20
100
N.A.
N.A.
6.6
13.3
73.3
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
0
100
N.A.
26.6
100
N.A.
N.A.
13.3
20
86.6
N.A.
N.A.
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.7
38
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.5
54.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
8
24
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% C
% Asp:
0
8
8
0
39
0
0
0
0
8
8
8
16
8
0
% D
% Glu:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
0
8
0
8
0
0
0
47
16
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
0
0
8
8
0
8
8
0
8
8
% K
% Leu:
8
0
0
16
0
0
16
16
0
39
0
31
0
0
8
% L
% Met:
0
0
8
31
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
8
8
0
8
0
0
0
0
% N
% Pro:
16
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
24
16
0
0
8
8
0
8
8
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
0
39
8
0
0
8
0
8
8
54
0
39
0
39
% S
% Thr:
0
39
0
0
0
8
0
8
0
8
8
8
8
0
0
% T
% Val:
0
8
0
0
0
8
0
8
8
0
0
16
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
16
24
8
62
54
39
47
16
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _