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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1E
All Species:
13.64
Human Site:
Y350
Identified Species:
25
UniProt:
Q12965
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12965
NP_004989.2
1108
127062
Y350
L
N
V
E
Q
A
C
Y
T
R
D
A
L
A
K
Chimpanzee
Pan troglodytes
XP_510448
1108
126943
Y350
L
N
V
E
Q
A
C
Y
T
R
D
A
L
A
K
Rhesus Macaque
Macaca mulatta
XP_001100995
715
80188
I33
P
Q
I
T
E
D
A
I
A
A
N
L
R
K
R
Dog
Lupus familis
XP_535500
1130
129758
Y372
L
N
V
E
Q
A
C
Y
T
R
D
A
L
A
K
Cat
Felis silvestris
Mouse
Mus musculus
P70248
1099
125929
A352
Q
A
A
Y
T
R
D
A
L
A
K
G
L
Y
A
Rat
Rattus norvegicus
Q63356
1107
126808
Y350
L
N
V
E
Q
A
C
Y
T
R
D
A
L
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLA6
1028
118889
L346
A
A
Y
A
R
D
A
L
A
K
A
I
Y
G
R
Frog
Xenopus laevis
NP_001080439
1094
125660
A352
Q
A
C
F
T
R
D
A
L
A
K
A
L
Y
S
Zebra Danio
Brachydanio rerio
XP_682849
1163
133360
F407
L
N
V
E
Q
A
C
F
T
R
D
A
L
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492393
1100
124867
A353
T
R
D
A
W
V
K
A
I
Y
A
R
L
F
D
Sea Urchin
Strong. purpuratus
NP_001118234
1118
127023
A350
A
H
T
R
D
A
L
A
K
A
V
H
S
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04439
1219
136881
A370
L
N
I
V
Q
A
D
A
V
R
D
A
L
A
K
Red Bread Mold
Neurospora crassa
Q7SDM3
1235
136290
R373
V
P
Q
A
T
A
T
R
D
A
L
A
M
A
I
Conservation
Percent
Protein Identity:
100
99.6
49.9
96.2
N.A.
70.4
95.6
N.A.
N.A.
35.8
75.5
77.7
N.A.
N.A.
N.A.
56.9
63.4
Protein Similarity:
100
99.8
56.5
97.4
N.A.
82
98
N.A.
N.A.
54.2
86.6
86.6
N.A.
N.A.
N.A.
71.7
78.7
P-Site Identity:
100
100
0
100
N.A.
6.6
100
N.A.
N.A.
0
13.3
86.6
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
6.6
100
N.A.
N.A.
20
13.3
100
N.A.
N.A.
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.7
38
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.5
54.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
24
8
24
0
62
16
39
16
39
16
62
0
47
8
% A
% Cys:
0
0
8
0
0
0
39
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
16
24
0
8
0
47
0
0
0
8
% D
% Glu:
0
0
0
39
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
16
0
0
0
0
8
8
0
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
8
0
8
8
16
0
0
8
47
% K
% Leu:
47
0
0
0
0
0
8
8
16
0
8
8
70
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
47
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
16
8
8
0
47
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
8
16
0
8
0
47
0
8
8
8
16
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
8
% S
% Thr:
8
0
8
8
24
0
8
0
39
0
0
0
0
0
0
% T
% Val:
8
0
39
8
0
8
0
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
31
0
8
0
0
8
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _