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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1E
All Species:
1.52
Human Site:
Y974
Identified Species:
2.78
UniProt:
Q12965
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12965
NP_004989.2
1108
127062
Y974
I
R
N
Q
Y
V
P
Y
P
H
A
P
G
S
Q
Chimpanzee
Pan troglodytes
XP_510448
1108
126943
H974
I
R
N
Q
Y
V
P
H
P
H
A
P
G
S
Q
Rhesus Macaque
Macaca mulatta
XP_001100995
715
80188
R596
M
S
G
G
S
S
H
R
P
P
R
G
P
P
S
Dog
Lupus familis
XP_535500
1130
129758
H996
I
K
N
Q
F
V
P
H
P
H
A
P
G
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
P70248
1099
125929
T969
P
R
G
E
G
P
Y
T
L
E
I
Y
I
W
P
Rat
Rattus norvegicus
Q63356
1107
126808
P973
T
R
N
Q
F
V
H
P
P
R
A
S
G
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLA6
1028
118889
Q909
S
R
Q
L
L
L
T
Q
N
A
V
I
I
V
E
Frog
Xenopus laevis
NP_001080439
1094
125660
L972
M
S
F
T
S
R
Q
L
S
V
E
Q
P
T
L
Zebra Danio
Brachydanio rerio
XP_682849
1163
133360
S1031
K
N
A
N
H
R
N
S
Q
H
H
N
N
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492393
1100
124867
P974
Q
A
M
R
A
P
V
P
A
H
G
M
N
N
N
Sea Urchin
Strong. purpuratus
NP_001118234
1118
127023
G965
A
P
S
Q
P
A
P
G
K
P
T
A
P
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04439
1219
136881
P1013
R
H
S
K
K
P
A
P
P
P
P
G
M
Q
N
Red Bread Mold
Neurospora crassa
Q7SDM3
1235
136290
G1010
R
T
A
Q
P
R
P
G
G
G
P
S
I
A
A
Conservation
Percent
Protein Identity:
100
99.6
49.9
96.2
N.A.
70.4
95.6
N.A.
N.A.
35.8
75.5
77.7
N.A.
N.A.
N.A.
56.9
63.4
Protein Similarity:
100
99.8
56.5
97.4
N.A.
82
98
N.A.
N.A.
54.2
86.6
86.6
N.A.
N.A.
N.A.
71.7
78.7
P-Site Identity:
100
93.3
6.6
73.3
N.A.
6.6
53.3
N.A.
N.A.
6.6
0
6.6
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
13.3
100
N.A.
13.3
66.6
N.A.
N.A.
20
13.3
20
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.7
38
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.5
54.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
16
0
8
8
8
0
8
8
31
8
0
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
8
8
0
0
0
8
% E
% Phe:
0
0
8
0
16
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
16
8
8
0
0
16
8
8
8
16
31
0
0
% G
% His:
0
8
0
0
8
0
16
16
0
39
8
0
0
0
0
% H
% Ile:
24
0
0
0
0
0
0
0
0
0
8
8
24
0
0
% I
% Lys:
8
8
0
8
8
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
8
8
0
8
8
0
0
0
0
0
8
% L
% Met:
16
0
8
0
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
8
31
8
0
0
8
0
8
0
0
8
16
24
16
% N
% Pro:
8
8
0
0
16
24
39
24
47
24
16
24
24
8
8
% P
% Gln:
8
0
8
47
0
0
8
8
8
0
0
8
0
16
31
% Q
% Arg:
16
39
0
8
0
24
0
8
0
8
8
0
0
0
8
% R
% Ser:
8
16
16
0
16
8
0
8
8
0
0
16
0
16
8
% S
% Thr:
8
8
0
8
0
0
8
8
0
0
8
0
0
8
0
% T
% Val:
0
0
0
0
0
31
8
0
0
8
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
16
0
8
8
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _