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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1E
All Species:
14.85
Human Site:
Y989
Identified Species:
27.22
UniProt:
Q12965
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12965
NP_004989.2
1108
127062
Y989
R
S
N
Q
K
S
L
Y
T
S
M
A
R
P
P
Chimpanzee
Pan troglodytes
XP_510448
1108
126943
Y989
R
S
N
Q
K
S
L
Y
T
S
M
A
R
P
P
Rhesus Macaque
Macaca mulatta
XP_001100995
715
80188
R611
T
S
L
G
A
S
R
R
P
R
A
Q
L
P
S
Dog
Lupus familis
XP_535500
1130
129758
Y1011
R
L
N
Q
K
S
L
Y
T
S
M
A
R
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P70248
1099
125929
T984
Q
E
F
P
E
A
S
T
A
I
H
L
Q
P
Q
Rat
Rattus norvegicus
Q63356
1107
126808
Y988
R
S
N
Q
K
S
L
Y
T
S
M
A
R
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLA6
1028
118889
I924
D
S
K
I
K
Q
R
I
D
Y
A
N
L
T
G
Frog
Xenopus laevis
NP_001080439
1094
125660
R987
P
R
Q
G
A
S
P
R
A
K
A
P
P
T
P
Zebra Danio
Brachydanio rerio
XP_682849
1163
133360
R1046
P
T
S
E
N
T
A
R
P
F
L
P
T
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492393
1100
124867
V989
Y
N
Q
T
P
A
P
V
S
T
N
H
Q
Y
S
Sea Urchin
Strong. purpuratus
NP_001118234
1118
127023
P980
L
V
Q
K
R
G
G
P
T
S
P
T
K
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04439
1219
136881
V1028
K
A
A
T
R
R
S
V
P
N
P
A
S
T
L
Red Bread Mold
Neurospora crassa
Q7SDM3
1235
136290
A1025
S
N
P
L
A
S
S
A
A
A
A
S
S
R
P
Conservation
Percent
Protein Identity:
100
99.6
49.9
96.2
N.A.
70.4
95.6
N.A.
N.A.
35.8
75.5
77.7
N.A.
N.A.
N.A.
56.9
63.4
Protein Similarity:
100
99.8
56.5
97.4
N.A.
82
98
N.A.
N.A.
54.2
86.6
86.6
N.A.
N.A.
N.A.
71.7
78.7
P-Site Identity:
100
100
20
93.3
N.A.
6.6
100
N.A.
N.A.
13.3
13.3
0
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
20
93.3
N.A.
33.3
100
N.A.
N.A.
13.3
13.3
33.3
N.A.
N.A.
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.7
38
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.5
54.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
24
16
8
8
24
8
31
39
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
16
0
8
8
0
0
0
0
0
0
8
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
0
8
0
0
0
0
0
% I
% Lys:
8
0
8
8
39
0
0
0
0
8
0
0
8
0
0
% K
% Leu:
8
8
8
8
0
0
31
0
0
0
8
8
16
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% M
% Asn:
0
16
31
0
8
0
0
0
0
8
8
8
0
8
0
% N
% Pro:
16
0
8
8
8
0
16
8
24
0
16
16
8
47
47
% P
% Gln:
8
0
24
31
0
8
0
0
0
0
0
8
16
0
8
% Q
% Arg:
31
8
0
0
16
8
16
24
0
8
0
0
31
8
0
% R
% Ser:
8
39
8
0
0
54
24
0
8
39
0
8
16
0
16
% S
% Thr:
8
8
0
16
0
8
0
8
39
8
0
8
8
24
0
% T
% Val:
0
8
0
0
0
0
0
16
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
31
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _