KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R8
All Species:
18.18
Human Site:
T346
Identified Species:
33.33
UniProt:
Q12972
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12972
NP_002704.1
351
38479
T346
A
W
P
G
K
K
P
T
P
S
L
L
I
_
_
Chimpanzee
Pan troglodytes
XP_001150604
378
41336
V346
A
W
P
G
C
E
F
V
S
Q
S
L
I
A
T
Rhesus Macaque
Macaca mulatta
XP_001112289
378
41328
V346
A
W
P
V
C
E
F
V
S
Q
S
L
I
A
T
Dog
Lupus familis
XP_865789
355
39236
T350
A
W
P
G
K
K
P
T
P
S
L
L
I
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3G1
351
38509
T346
A
W
P
G
K
K
P
T
P
S
L
L
I
_
_
Rat
Rattus norvegicus
NP_001101381
351
38521
T346
A
W
P
G
K
K
P
T
P
S
L
L
I
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518825
234
26189
Chicken
Gallus gallus
NP_001026062
354
38600
N347
G
M
A
G
Q
E
A
N
P
F
S
T
D
L
S
Frog
Xenopus laevis
NP_001083528
346
37932
T341
A
W
P
G
K
K
P
T
P
S
L
L
I
_
_
Zebra Danio
Brachydanio rerio
NP_001094422
351
38384
K343
A
K
E
A
W
P
G
K
K
P
T
P
S
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611177
383
42555
L337
T
S
T
L
A
Q
K
L
A
V
A
N
A
N
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492781
302
33933
Sea Urchin
Strong. purpuratus
XP_001199058
347
38163
Q341
E
A
W
P
G
K
K
Q
A
P
S
L
L
L
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.8
91.2
89
N.A.
98
97.7
N.A.
65.8
88.6
82.9
77.7
N.A.
47.5
N.A.
39
51.5
Protein Similarity:
100
91.8
91.5
90.4
N.A.
98.5
98.5
N.A.
66
93.2
89.7
88
N.A.
62.1
N.A.
53.8
67.5
P-Site Identity:
100
40
33.3
100
N.A.
100
100
N.A.
0
13.3
100
6.6
N.A.
0
N.A.
0
14.2
P-Site Similarity:
100
46.6
40
100
N.A.
100
100
N.A.
0
26.6
100
6.6
N.A.
6.6
N.A.
0
21.4
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
62
8
8
8
8
0
8
0
16
0
8
0
8
16
0
% A
% Cys:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
8
0
8
0
0
24
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
16
0
0
8
0
0
0
0
0
% F
% Gly:
8
0
0
54
8
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
54
0
0
% I
% Lys:
0
8
0
0
39
47
16
8
8
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
8
0
0
39
62
8
24
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
0
% N
% Pro:
0
0
54
8
0
8
39
0
47
16
0
8
0
0
0
% P
% Gln:
0
0
0
0
8
8
0
8
0
16
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
16
39
31
0
8
0
8
% S
% Thr:
8
0
8
0
0
0
0
39
0
0
8
8
0
0
16
% T
% Val:
0
0
0
8
0
0
0
16
0
8
0
0
0
0
8
% V
% Trp:
0
54
8
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
47
% _