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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTP4A2 All Species: 41.21
Human Site: T26 Identified Species: 90.67
UniProt: Q12974 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12974 NP_536316.1 167 19127 T26 T H N P T N A T L N K F T E E
Chimpanzee Pan troglodytes XP_511509 167 19142 T26 T H N P T N A T L N K F T E E
Rhesus Macaque Macaca mulatta XP_001100815 167 18998 T26 T H N P T N A T L N K F T E K
Dog Lupus familis XP_852076 167 19061 T26 T H N P T N A T L N K F T E E
Cat Felis silvestris
Mouse Mus musculus Q9D658 173 19633 T29 T H N P S N A T L S T F I E D
Rat Rattus norvegicus Q6P9X4 167 19109 T26 T H N P T N A T L N K F T E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506703 167 19073 T26 T H N P T N A T L N K F T E E
Chicken Gallus gallus XP_001233322 167 19007 T26 T H N P T N A T L C R F I E E
Frog Xenopus laevis NP_001080240 167 19055 T26 T H N P T N A T L N K F T E E
Zebra Danio Brachydanio rerio NP_001007776 173 19985 T29 T H N P T N A T L H K F I E E
Tiger Blowfish Takifugu rubipres P0C599 210 23683 Y24 R V D P D S D Y I T P G T L D
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 92.2 99.4 N.A. 75.1 100 N.A. 97 92.2 94 84.9 22.3 N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.5 94 99.4 N.A. 85.5 100 N.A. 98.8 95.8 96.4 90.7 37.1 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 100 N.A. 66.6 100 N.A. 100 80 100 86.6 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 100 N.A. 100 86.6 100 93.3 40 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 91 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 10 0 10 0 10 0 0 0 0 0 0 0 19 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 91 73 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 91 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 91 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 28 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 73 0 0 0 10 % K
% Leu: 0 0 0 0 0 0 0 0 91 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 91 0 0 91 0 0 0 64 0 0 0 0 0 % N
% Pro: 0 0 0 100 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 0 0 0 10 10 0 0 0 10 0 0 0 0 0 % S
% Thr: 91 0 0 0 82 0 0 91 0 10 10 0 73 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _