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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTP4A2
All Species:
37.27
Human Site:
Y50
Identified Species:
82
UniProt:
Q12974
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12974
NP_536316.1
167
19127
Y50
V
R
V
C
D
A
T
Y
D
K
A
P
V
E
K
Chimpanzee
Pan troglodytes
XP_511509
167
19142
Y50
V
R
V
C
D
A
T
Y
D
K
A
P
V
X
K
Rhesus Macaque
Macaca mulatta
XP_001100815
167
18998
Y50
S
S
V
S
X
X
T
Y
D
K
A
P
V
E
K
Dog
Lupus familis
XP_852076
167
19061
Y50
V
R
V
C
D
A
T
Y
D
K
A
P
V
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D658
173
19633
Y53
V
R
V
C
E
V
T
Y
D
K
T
P
L
E
K
Rat
Rattus norvegicus
Q6P9X4
167
19109
Y50
V
R
V
C
D
A
T
Y
D
K
A
P
V
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506703
167
19073
Y50
V
R
V
C
D
A
T
Y
D
K
A
P
I
E
K
Chicken
Gallus gallus
XP_001233322
167
19007
Y50
V
R
V
C
D
A
T
Y
D
K
A
P
I
E
K
Frog
Xenopus laevis
NP_001080240
167
19055
Y50
V
R
V
C
D
A
T
Y
D
K
A
P
V
E
K
Zebra Danio
Brachydanio rerio
NP_001007776
173
19985
Y53
V
R
V
C
E
A
T
Y
D
A
N
L
V
V
K
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
N48
G
V
Q
Y
T
H
V
N
Q
V
W
P
G
I
Y
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
92.2
99.4
N.A.
75.1
100
N.A.
97
92.2
94
84.9
22.3
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.5
94
99.4
N.A.
85.5
100
N.A.
98.8
95.8
96.4
90.7
37.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
66.6
100
N.A.
73.3
100
N.A.
93.3
93.3
100
66.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
66.6
100
N.A.
86.6
100
N.A.
100
100
100
73.3
6.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
73
0
0
0
10
73
0
0
0
0
% A
% Cys:
0
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
64
0
0
0
91
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
19
0
0
0
0
0
0
0
0
73
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
19
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
82
0
0
0
0
91
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
91
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
82
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
91
0
0
0
10
0
0
0
0
% T
% Val:
82
10
91
0
0
10
10
0
0
10
0
0
64
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
91
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _