KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARE
All Species:
23.64
Human Site:
S189
Identified Species:
40
UniProt:
Q12980
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12980
NP_001070818.1
569
63605
S189
D
G
N
E
G
P
Q
S
P
F
H
H
I
L
P
Chimpanzee
Pan troglodytes
XP_510703
569
63558
S189
D
G
N
E
G
P
Q
S
P
F
H
H
I
L
P
Rhesus Macaque
Macaca mulatta
XP_001118432
569
63094
S189
D
G
D
K
G
D
R
S
P
F
H
H
I
L
P
Dog
Lupus familis
XP_854363
368
40934
N21
G
V
V
R
L
H
I
N
S
W
L
E
V
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIJ8
569
63599
S189
D
A
N
E
G
P
Q
S
P
F
Q
H
I
L
P
Rat
Rattus norvegicus
NP_001030108
469
52283
I122
K
R
E
A
P
T
M
I
L
F
N
V
V
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517960
146
16314
Chicken
Gallus gallus
XP_414946
569
63971
S189
E
T
T
E
G
P
Q
S
P
F
H
H
I
L
P
Frog
Xenopus laevis
NP_001083270
580
64646
S200
E
T
N
G
G
P
Q
S
P
F
H
H
I
L
P
Zebra Danio
Brachydanio rerio
NP_001020705
596
67120
S216
D
S
D
G
S
P
Q
S
P
F
R
Q
I
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUB4
610
68769
I195
L
E
R
T
L
E
L
I
A
E
R
C
S
L
A
Honey Bee
Apis mellifera
XP_395986
511
58454
I164
C
G
F
L
T
E
E
I
K
I
M
V
S
T
H
Nematode Worm
Caenorhab. elegans
Q20069
511
57899
F164
L
V
M
L
Q
N
Y
F
G
F
L
E
R
E
D
Sea Urchin
Strong. purpuratus
XP_792244
494
55249
L147
Q
A
S
A
D
W
S
L
V
H
C
Y
Q
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
91.9
63
N.A.
96.3
77.5
N.A.
23.2
87.5
81.5
75.3
N.A.
37.3
41.4
21.4
39.8
Protein Similarity:
100
100
94.1
63.7
N.A.
98.2
79.4
N.A.
24.7
94.7
89.4
83.5
N.A.
56.3
61.3
42
57.8
P-Site Identity:
100
100
73.3
0
N.A.
86.6
6.6
N.A.
0
80
80
60
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
93.3
20
N.A.
86.6
20
N.A.
0
86.6
86.6
66.6
N.A.
6.6
13.3
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
15
0
0
0
0
8
0
0
0
0
0
15
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% C
% Asp:
36
0
15
0
8
8
0
0
0
0
0
0
0
8
8
% D
% Glu:
15
8
8
29
0
15
8
0
0
8
0
15
0
8
0
% E
% Phe:
0
0
8
0
0
0
0
8
0
65
0
0
0
8
8
% F
% Gly:
8
29
0
15
43
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
8
36
43
0
0
8
% H
% Ile:
0
0
0
0
0
0
8
22
0
8
0
0
50
0
0
% I
% Lys:
8
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
15
0
0
15
15
0
8
8
8
0
15
0
0
58
8
% L
% Met:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
29
0
0
8
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
8
43
0
0
50
0
0
0
0
0
50
% P
% Gln:
8
0
0
0
8
0
43
0
0
0
8
8
8
0
0
% Q
% Arg:
0
8
8
8
0
0
8
0
0
0
15
0
8
0
0
% R
% Ser:
0
8
8
0
8
0
8
50
8
0
0
0
15
8
0
% S
% Thr:
0
15
8
8
8
8
0
0
0
0
0
0
0
8
0
% T
% Val:
0
15
8
0
0
0
0
0
8
0
0
15
15
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _